MOG
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Official Full Name
myelin oligodendrocyte glycoprotein
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Overview
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface;of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination.;This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication.;Alternatively spliced transcript variants encoding different isoforms have been identified. -
Synonyms
MOG; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; MOG Ig-AluB; MOG alpha-5; MOGIG2; NRCLP7; MGC26137;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Protein Pre-coupled Magnetic Beads
- Native Proteins
- Bos taurus (Bovine)
- Callithrix jacchus (White-tufted-ear marmoset)
- Cattle
- Cynomolgus Monkey
- Human
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Mouse
- Mouse/Rat
- Mus musculus (Mouse)
- Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
- Rat
- Rattus norvegicus (Rat)
- E. coli
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- NS0
- Rabbit
- Synthetic
- Wheat Germ
- C
- 6×His
- GFP
- His
- Fc
- GST
- HIS
- His (Fc)
- Avi
- Myc
- DDK
- Myc|DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- MOG Related Articles
- MOG Related Research Area
MOG involved in several pathways and played different roles in them. We selected most pathways MOG participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MOG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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MOG has several biochemical functions, for example, virus receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MOG itself. We selected most functions MOG had, and list some proteins which have the same functions with MOG. You can find most of the proteins on our site.
Function | Related Protein |
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virus receptor activity | EFNB3;MOG;ITGB3;PVRL4;CR2;ICAM1;CD209;LDLR;MRC1 |
MOG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOG here. Most of them are supplied by our site. Hope this information will be useful for your research of MOG.
OTUD4
- Q&As
- Reviews
Q&As (7)
Ask a questionMOG is predominantly expressed on the outer surface of the myelin sheath in the central nervous system.
MOG is a target in autoimmune demyelinating diseases, where the immune system mistakenly attacks it, damaging the myelin sheath.
MOG antibody testing helps diagnose and distinguish different demyelinating diseases, and therapies aim to modulate the immune response to prevent MOG attack.
There are no widely recognized genetic mutations in MOG associated with neurological conditions, but research is ongoing.
MOG contributes to myelin integrity, aiding in proper nerve signal transmission.
MOG antibodies are found in a subset of MS patients, but their exact role in MS pathogenesis is still under investigation.
MOG is involved in the maintenance and stability of the myelin sheath in the central nervous system.
Customer Reviews (3)
Write a reviewExcellent in protein studies.
Reliable, efficient, and effective.
Worked well, great quality.
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