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MOGAT1

  • Official Full Name

    monoacylglycerol O-acyltransferase 1

  • Overview

    Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerols, the;precursor of physiologically important lipids such as triacylglycerol and phospholipids (Yen et al., 2002 (PubMed;12077311)).
  • Synonyms

    MOGAT1; monoacylglycerol O-acyltransferase 1; DGAT2L1, diacylglycerol O acyltransferase 2 like 1; 2-acylglycerol O-acyltransferase 1; DGAT2L; MGAT1; 1110064N14Rik; Diacylglycerol O acyltransferase 2 like 1; MGC118035; 0610030A14Rik; Acyl CoA:monoacylglycerol acyltransferase 1; DGAT2L1; Diacylglycerol acyltransferase 2 like; Diacylglycerol O-acyltransferase candidate 2; hDC2; mDC2; Monoacylglycerol O acyltransferase 1; OTTMUSP00000025181; diacylglycerol O-acyltransferase 2 like 1; acyl-CoA:monoacylglycerol acyltransferase 1; diacylglycerol acyltransferase 2-like protein 1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Xenopus laevis (African clawed frog)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MOGAT1-1127HCL Recombinant Human MOGAT1 cell lysate N/A
Human MOGAT1-5467H Recombinant Human MOGAT1 Protein, GST-tagged Wheat Germ GST
Human MOGAT1-6303HF Recombinant Full Length Human MOGAT1 Protein, GST-tagged In Vitro Cell Free System GST 334 amino acids
Human MOGAT1-3996H Recombinant Human MOGAT1 Protein (Arg153-Lys335), N-His tagged E.coli N-His Arg153-Lys335
Mouse MOGAT1-9952M Recombinant Mouse MOGAT1 Protein Mammalian Cell His
Mouse MOGAT1-5625M Recombinant Mouse MOGAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MOGAT1-5625M-B Recombinant Mouse MOGAT1 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL5476BF Recombinant Full Length Bovine 2-Acylglycerol O-Acyltransferase 1(Mogat1) Protein, His-Tagged E.coli expression system His Full Length (1-335)
Homo sapiens (Human) RFL16306HF Recombinant Full Length Human 2-Acylglycerol O-Acyltransferase 1(Mogat1) Protein, His-Tagged E.coli expression system His Full Length (1-335)
Mus musculus (Mouse) RFL27067MF Recombinant Full Length Mouse 2-Acylglycerol O-Acyltransferase 1(Mogat1) Protein, His-Tagged E.coli expression system His Full Length (1-335)
Xenopus laevis (African clawed frog) RFL34783XF Recombinant Full Length Xenopus Laevis 2-Acylglycerol O-Acyltransferase 1(Mogat1) Protein, His-Tagged E.coli expression system His Full Length (1-335)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL514XF Recombinant Full Length Xenopus Tropicalis 2-Acylglycerol O-Acyltransferase 1(Mogat1) Protein, His-Tagged E.coli expression system His Full Length (1-335)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MOGAT1 Related Articles

MOGAT1 involved in several pathways and played different roles in them. We selected most pathways MOGAT1 participated on our site, such as Glycerolipid metabolism, Triacylglyceride Synthesis, triacylglycerol biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with MOGAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerolipid metabolismPNLIPRP1;AKR1B10;Cel;AGPAT9;GK;ALDH2.1;PNLIPRP3;DGAT1;PNLIPRP2
Triacylglyceride Synthesis
triacylglycerol biosynthesisPPAPDC1A;MOGAT1;LPPR3;LPPR2

MOGAT1 has several biochemical functions, for example, 2-acylglycerol O-acyltransferase activity, diacylglycerol O-acyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MOGAT1 itself. We selected most functions MOGAT1 had, and list some proteins which have the same functions with MOGAT1. You can find most of the proteins on our site.

Function Related Protein
2-acylglycerol O-acyltransferase activityDGAT2;DGAT1;MOGAT3;MOGAT1
diacylglycerol O-acyltransferase activityDGAT1B;DGAT1;DGAT2;DGAT1A;MOGAT3;MOGAT1

MOGAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOGAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MOGAT1.

McIntosh, AL; Huang, H; et al. Human FABP1 T94A variant impacts fatty acid metabolism and PPAR-alpha activation in cultured human female hepatocytes. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 307:G164-G176(2014).
Jeon, S; Park, YJ; et al. Genistein alleviates the development of nonalcoholic steatohepatitis in ApoE-/- mice fed a high- fat diet. MOLECULAR NUTRITION & FOOD RESEARCH 58:830-841(2014).
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