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MORF4L2

  • Official Full Name

    mortality factor 4 like 2

  • Overview

    Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
  • Synonyms

    MORF4L2; mortality factor 4 like 2; mortality factor 4-like protein 2; KIAA0026; MORF related gene X; MRGX; MO4L2_HUMAN; MORF related gene X protein; MORF-related gene X protein; MORFL2; Mortality factor 4 like protein 2; MSL3 2 protein; Protein MSL3-2; Transcription factor like protein MRGX; Transcription factor-like protein MRGX; MSL3-2 protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MORF4L2-3492H Recombinant Human MORF4L2, His-tagged E.coli His
Human MORF4L2-29353TH Recombinant Human MORF4L2, His-tagged E.coli His 288 amino acids
Human MORF4L2-4251HCL Recombinant Human MORF4L2 293 Cell Lysate HEK293 N/A
Human MORF4L2-5747H Recombinant Human MORF4L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MORF4L2-5479H Recombinant Human MORF4L2 Protein, GST-tagged Wheat Germ GST
Human MORF4L2-1399H Recombinant Human MORF4L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MORF4L2-5361H Recombinant Human MORF4L2 Protein (Met1-Leu288), C-His tagged E.coli C-His Met1-Leu288
Human MORF4L2-6458H Recombinant Human MORF4L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MORF4L2-3529H Recombinant Human MORF4L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MORF4L2-6310HF Recombinant Full Length Human MORF4L2 Protein, GST-tagged In Vitro Cell Free System GST 288 amino acids
Human MORF4L2-4215H Recombinant Human MORF4L2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse MORF4L2-9964M Recombinant Mouse MORF4L2 Protein Mammalian Cell His
Mouse MORF4L2-5636M-B Recombinant Mouse MORF4L2 Protein Pre-coupled Magnetic Beads HEK293
Mouse MORF4L2-5636M Recombinant Mouse MORF4L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Morf4l2-4115M Recombinant Mouse Morf4l2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat MORF4L2-3728R Recombinant Rat MORF4L2 Protein Mammalian Cell His
Rat MORF4L2-3386R-B Recombinant Rat MORF4L2 Protein Pre-coupled Magnetic Beads HEK293
Rat MORF4L2-3386R Recombinant Rat MORF4L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey MORF4L2-700C Recombinant Cynomolgus MORF4L2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey MORF4L2-446C-B Recombinant Cynomolgus Monkey MORF4L2 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey MORF4L2-446C Recombinant Cynomolgus Monkey MORF4L2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MORF4L2 Related Articles
  • MORF4L2 Related Research Area

MORF4L2 involved in several pathways and played different roles in them. We selected most pathways MORF4L2 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with MORF4L2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesDMAP1;RUVBL2;SMARCD3;KDM6AL;KDM7AB;MBIP;EP400;KDM5BB;ARID1A
Chromatin organizationUSP22;KDM6AL;MSL3;RBBP5;KDM3B;TADA1;MSL2B;CAPNS2;YEATS4
HATs acetylate histonesING5B;CCDC101;CAPNS2;MCRS1;CSRP2BP;MBIP;ING3;ELP2;ING5

MORF4L2 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MORF4L2 itself. We selected most functions MORF4L2 had, and list some proteins which have the same functions with MORF4L2. You can find most of the proteins on our site.

Function Related Protein
protein bindingANKRD54;NUPL1;ADAMTS10;TMEM190;TUBA1A;IPO4;RANBP6;FAM72A;LRRC20

MORF4L2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MORF4L2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MORF4L2.

MRGBP; MRFAP1; CDR2

Vogt, LM; Meyer, D; et al. Toll-Like Receptor 2 Activation by beta 2 -> 1-Fructans Protects Barrier Function of T84 Human Intestinal Epithelial Cells in a Chain Length-Dependent Manner. JOURNAL OF NUTRITION 144:1002-1008(2014).
Chantratita, N; Tandhavanant, S; et al. Survey of Innate Immune Responses to Burkholderia pseudomallei in Human Blood Identifies a Central Role for Lipopolysaccharide. PLOS ONE 8:-(2013).
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