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MOS

  • Official Full Name

    v-mos Moloney murine sarcoma viral oncogene homolog

  • Overview

    MOS is a serine/threonine kinase that activates the MAP kinase cascade through direct phosphorylation of the MAP kinase;activator MEK (MAP2K1; MIM 176872) (Prasad et al., 2008 (PubMed 18246541)).
  • Synonyms

    MOS; v-mos Moloney murine sarcoma viral oncogene homolog; proto-oncogene serine/threonine-protein kinase mos; c-mos; proto-oncogene c-Mos; oocyte maturation factor mos; oncogene MOS, Moloney murine sarcoma virus; MSV; MGC119962; MGC119963;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Chicken
  • Human
  • Zebrafish
  • HEK293
  • In Vitro Cell Free System
  • Insect (sf21)
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MOS-4247HCL Recombinant Human MOS 293 Cell Lysate HEK293 N/A
Human MOS-5485H Recombinant Human MOS Protein, GST-tagged Wheat Germ GST
Human MOS-5484H Active Recombinant Human MOS Protein, GST-tagged Insect Cell GST
Human MOS-6314HF Recombinant Full Length Human MOS Protein, GST-tagged In Vitro Cell Free System GST 346 amino acids
Human MOS-6055HF Active Recombinant Full Length Human MOS Protein, GST-tagged Insect (sf21) GST 1-346
Zebrafish MOS-11620Z Recombinant Zebrafish MOS Mammalian Cell His
Chicken MOS-3161C Recombinant Chicken MOS Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MOS Related Articles
  • MOS Related Research Area

MOS involved in several pathways and played different roles in them. We selected most pathways MOS participated on our site, such as MAPK signaling pathway, Oocyte meiosis, Regulation of actin cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with MOS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayPPP3R1B;PRKCB;LRRK2;CACNA1SA;RPS6KA2;HRASA;MAPKAPK2A;RRAS2;PPM1AA
Oocyte meiosisCPEB2;CAMK2A;IGF1R;PTTG1;FBXO43;RPS6KA1;YWHAE2;PPP2R5CB;ADCY2B
Regulation of actin cytoskeletonPAK2B;PIK3R3A;SSH3;PIP5K1C;PPP1CAA;CD14;MYL1;PDGFRA;ITGB7
Progesterone-mediated oocyte maturationINS;INSB;ANAPC2;MAPK8;HSP90AA1.1;PRKACA;PIK3R3;SPDYB;PIK3CA

MOS has several biochemical functions, for example, ATP binding, MAP kinase kinase kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MOS itself. We selected most functions MOS had, and list some proteins which have the same functions with MOS. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMAPK13;MTHFS;OLA1;MTPAP;RAF1B;RTEL1;MCCC1;MARK2;PTK7
MAP kinase kinase kinase activityALPK2;MAP3K5;TAOK1;YSK4;MAP3K2;MAP3K3;KIAA1804;ZAK;MAP3K6
protein bindingNRCAM;ACE2;ISCU;SPRR2E;ACTL7A;PRKAA2;EDN1;RYR1;WHSC1
protein serine/threonine kinase activityCLK4;ROCK2A;RIPK2;CSNK1G1;CSNK2A1;MAP2K4;MAPK14;TAOK1;STK32A

MOS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MOS here. Most of them are supplied by our site. Hope this information will be useful for your research of MOS.

KRT13; CCDC102B; HOMER3; 80125; CCNDBP1; GFAP; TRIM27

Shan, LF; Li, M; et al. PCR-Based Assays versus Direct Sequencing for Evaluating the Effect of KRAS Status on Anti-EGFR Treatment Response in Colorectal Cancer Patients: A Systematic Review and Meta-Analysis. PLOS ONE 9:-(2014).
Liu, X; Byrd, JA; et al. Arginine and vitamin E improve the immune response after a Salmonella challenge in broiler chicks. POULTRY SCIENCE 93:882-890(2014).
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