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MPST

  • Official Full Name

    mercaptopyruvate sulfurtransferase

  • Overview

    This protein encoded by this gene catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST, GeneID:7263), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU). Alternatively spliced transcript variants encoding same or different isoforms have been identified for this gene.
  • Synonyms

    MPST; mercaptopyruvate sulfurtransferase; 3-mercaptopyruvate sulfurtransferase; human liver rhodanese; MST; TST2; 3 mercaptopyruvate sulfurtransferase; MGC24539; THTM_HUMAN; OTTHUMP00000197786; OTTHUMP00000197787; OTTHUMP00000197788; OTTHUMP00000197789; OTTHUMP00000197791;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MPST-30249TH Recombinant Human MPST Wheat Germ N/A 100 amino acids
Human MPST-7078H Recombinant Human MPST, His-tagged E.coli His 1-297aa
Human MPST-29702TH Recombinant Human MPST Wheat Germ N/A 297 amino acids
Human MPST-4224HCL Recombinant Human MPST 293 Cell Lysate HEK293 N/A
Human MPST-4223HCL Recombinant Human MPST 293 Cell Lysate HEK293 N/A
Human MPST-536H Recombinant Human MPST Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MPST-311HF Recombinant Full Length Human MPST Protein In Vitro Cell Free System 297 amino acids
Human MPST-5520H Recombinant Human MPST Protein, GST-tagged Wheat Germ GST
Human MPST-3211H Recombinant Human MPST Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MPST-4213H Recombinant Human MPST Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MPST-4598H Recombinant Human MPST Protein (Met1-Ala156), N-His tagged E.coli N-His Met1-Ala156
Human MPST-5436H Recombinant Human MPST Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MPST-6334HF Recombinant Full Length Human MPST Protein, GST-tagged In Vitro Cell Free System GST 297 amino acids
Mouse Mpst-7956M Recombinant Mouse Mpst protein, His & T7-tagged E.coli His/T7 Met1~Gln297 (Accession # Q99J99)
Mouse Mpst-4129M Recombinant Mouse Mpst Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat MPST-3741R Recombinant Rat MPST Protein Mammalian Cell His
Rat MPST-3399R Recombinant Rat MPST Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MPST-3399R-B Recombinant Rat MPST Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MPST-2817R Recombinant Rhesus monkey MPST Protein, His-tagged Mammalian Cell His
Rhesus Macaque MPST-2637R-B Recombinant Rhesus Macaque MPST Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MPST-2637R Recombinant Rhesus Macaque MPST Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken MPST-4791C Recombinant Chicken MPST Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MPST Related Articles

MPST involved in several pathways and played different roles in them. We selected most pathways MPST participated on our site, such as Cysteine and methionine metabolism, Sulfur metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with MPST were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cysteine and methionine metabolismMAT2AB;MPST;DNMT3A;BCAT1;LDHAL6A;SDS;TST;DNMT3AB;MAT1A
Sulfur metabolismSQRDL;MPST;IMPAD1;CYCS;PAPSS2A;PAPSS1;TST;PAPSS2B;SUOX
Metabolic pathwaysB3GNT5A;PIGYL;PLCE1;CECR1;POLR2G;KMO;HIBCH;INPP4AB;BCMO1
Sulfur relay systemTRMU;CTU2;CTU1;LBH;URM1;MPST;MOCS1;MOCS3;TST

MPST has several biochemical functions, for example, 3-mercaptopyruvate sulfurtransferase activity, identical protein binding, thiosulfate sulfurtransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MPST itself. We selected most functions MPST had, and list some proteins which have the same functions with MPST. You can find most of the proteins on our site.

Function Related Protein
3-mercaptopyruvate sulfurtransferase activity
identical protein bindingAKT1;Serpina1b;MVK;UHRF1;DVL1;ATG101;VEGFA;SRI;TRIM21
thiosulfate sulfurtransferase activityTST;MOCS3;MPST

MPST has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPST here. Most of them are supplied by our site. Hope this information will be useful for your research of MPST.

CHM; TFAP2A

Bauer, M; Dietrich, C; et al. Intracellular localization of Arabidopsis sulfurtransferases. PLANT PHYSIOLOGY 135:916-926(2004).
Papenbrock, J; Schmidt, A; et al. Characterization of two sulfurtransferase isozymes from Arabidopsis thaliana. EUROPEAN JOURNAL OF BIOCHEMISTRY 267:5571-5579(2000).
  • Q&As
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