Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

MRPS11

Official Full Name

mitochondrial ribosomal protein S11
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms.
Synonyms

MRPS11; mitochondrial ribosomal protein S11; 28S ribosomal protein S11, mitochondrial; cervical cancer proto oncogene 2; FLJ22512; FLJ23406; HCC 2; mitochondrial; 28S ribosomal protein S11; 28S ribosomal protein S11, mitochondrial precursor; Cervical cancer proto oncogene 2 protein; Cervical cancer proto-oncogene 2 protein; HCC-2; MRP S11; MRP-S11; RPMS11; RT11_HUMAN; S11mt;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPS11-28172TH	Recombinant Human MRPS11, His-tagged	E.coli	His		Inquiry
Human	MRPS11-4153HCL	Recombinant Human MRPS11 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MRPS11-5600H	Recombinant Human MRPS11 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MRPS11-6455HF	Recombinant Full Length Human MRPS11 Protein, GST-tagged	In Vitro Cell Free System	GST	194 amino acids	Inquiry
Mouse	Mrps11-4164M	Recombinant Mouse Mrps11 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rhesus Macaque	MRPS11-2854R	Recombinant Rhesus monkey MRPS11 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	MRPS11-2674R	Recombinant Rhesus Macaque MRPS11 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	MRPS11-2674R-B	Recombinant Rhesus Macaque MRPS11 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	MRPS11-3936Z	Recombinant Zebrafish MRPS11	Mammalian Cell	His		Inquiry
Chicken	MRPS11-1261C	Recombinant Chicken MRPS11	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MRPS11 Related Articles

MRPS11 involved in several pathways and played different roles in them. We selected most pathways MRPS11 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome	MRPL35;RPS27A;MRPL3;RPS19;RPL11;RPL14;RPL19;MRPL22;MRPL11

MRPS11 has several biochemical functions, for example, mRNA 5-UTR binding, poly(A) RNA binding, small ribosomal subunit rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS11 itself. We selected most functions MRPS11 had, and list some proteins which have the same functions with MRPS11. You can find most of the proteins on our site.

Function	Related Protein
mRNA 5-UTR binding	RPS14;IGF2BP3;IGF2BP1;MRPS11;IGF2BP2;LARP1;DDX3X
poly(A) RNA binding	SNIP1;PES1;ALDH18A1;RBM25;TCOF1;DZIP3;EZR;RSRC2;SF3B4
small ribosomal subunit rRNA binding	NSUN4;RPS14;MRPS11;RPS3;MRPS6;CIRBP;UTP23;RPS13
structural constituent of ribosome	RPL13A;MRPL36;SLC25A24L;RPS12;RPL28;FAU;RPS5;RPS14;RPL29

MRPS11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS11.

SRPK2; SRPK1; ssdna_dtdc; ICT1; SLX4; MAP1LC3A

Choi, SJ; Park, EJ; et al. Inheritance pattern of chloroplast and mitochondrial genomes in artificial hybrids of Porphyra yezoensis (Rhodophyta). FISHERIES SCIENCE 74:822-829(2008).

Zikova, A; Panigrahi, AK; et al. Trypanosoma brucei mitochondrial ribosomes. MOLECULAR & CELLULAR PROTEOMICS 7:1286-1296(2008).