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MRPS15

Official Full Name

mitochondrial ribosomal protein S15
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.
Synonyms

MRPS15; mitochondrial ribosomal protein S15; 28S ribosomal protein S15, mitochondrial; FLJ11564; MRP-S15; DC37; S15mt; RPMS15; MPR-S15;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPS15-1108H	Recombinant Human MRPS15	Mammalian Cell	His		Inquiry
Human	MRPS15-1021H	Recombinant Human MRPS15, GST-tagged	E.coli	GST	1-257aa	$319 / 25ug
Human	MRPS15-4150HCL	Recombinant Human MRPS15 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MRPS15-3523H	Recombinant Human MRPS15 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	MRPS15-1942H	Recombinant Human MRPS15 Protein, His-tagged	E.coli	His		Inquiry
Human	MRPS15-5603H	Recombinant Human MRPS15 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MRPS15-6467HF	Recombinant Full Length Human MRPS15 Protein, GST-tagged	In Vitro Cell Free System	GST	257 amino acids	Inquiry
Human	MRPS15-3523H-B	Recombinant Human MRPS15 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	MRPS15-3778R	Recombinant Rat MRPS15 Protein	Mammalian Cell	His		Inquiry
Rat	MRPS15-3437R	Recombinant Rat MRPS15 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MRPS15-3437R-B	Recombinant Rat MRPS15 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	MRPS15-613Z	Recombinant Zebrafish MRPS15	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MRPS15 involved in several pathways and played different roles in them. We selected most pathways MRPS15 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome	RPL11;MRPS10;RPS15A;MRPL12;RPL36A;MRPS9;RPL27;MRPL3;RPL23

MRPS15 has several biochemical functions, for example, poly(A) RNA binding, structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS15 itself. We selected most functions MRPS15 had, and list some proteins which have the same functions with MRPS15. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	RPS9;RPS4Y1;RPUSD2;TBL2;RTCA;PPIB;ELAVL2;PSIP1;RPL11
structural constituent of ribosome	RPL10;RPS17L;MRPL18;RPL36A;RPL13A;MRPL37;RPS11;RPS15;RPL35A

MRPS15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS15 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS15.

ESR2; PTCD3; Brwd3; ssrna_ug; ACSL4; ESR1; Nfyc; MPP1; HNRNPU; ORC1; ICT1; Prmt6; CDC73; Pcgf1; MRPS27; VPS16; AGO1; PHF8