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MRPS31

  • Official Full Name

    mitochondrial ribosomal protein S31

  • Overview

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
  • Synonyms

    MRPS31; mitochondrial ribosomal protein S31; 28S ribosomal protein S31, mitochondrial; IMOGN38; Imogen 38; S31mt; MRP-S31;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MRPS31-1036H Recombinant Human MRPS31, GST-tagged E.coli GST 63-395aa
Human MRPS31-1136HCL Recombinant Human MRPS31 cell lysate N/A
Human MRPS31-6501HF Recombinant Full Length Human MRPS31 Protein, GST-tagged In Vitro Cell Free System GST 395 amino acids
Human MRPS31-1936H Recombinant Human MRPS31 Protein, His-tagged E.coli His
Human MRPS31-5619H Recombinant Human MRPS31 Protein, GST-tagged Wheat Germ GST
Mouse MRPS31-10101M Recombinant Mouse MRPS31 Protein Mammalian Cell His
Mouse MRPS31-5725M Recombinant Mouse MRPS31 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MRPS31-5725M-B Recombinant Mouse MRPS31 Protein Pre-coupled Magnetic Beads HEK293
Rat MRPS31-3781R Recombinant Rat MRPS31 Protein Mammalian Cell His
Rat MRPS31-3440R Recombinant Rat MRPS31 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MRPS31-3440R-B Recombinant Rat MRPS31 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MRPS31-6844Z Recombinant Zebrafish MRPS31 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MRPS31 involved in several pathways and played different roles in them. We selected most pathways MRPS31 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS31 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Mitochondrial translationMRPL46;DAP3;GFM2;CHCHD1;MRPL47;MRPL50;MRPS28;ICT1;GFM1
Mitochondrial translation elongationMRPL39;MRPL37;TUFM;MRPS33;MRPL51;MRPL48;MRPL45;MRPL47;MRPL54
Mitochondrial translation initiationMRPL51;MRPS31;MRPL48;GADD45GIP1;MRPS24;MRPS35;MRPL37;MRPL28;MRPL38
Mitochondrial translation terminationMRRF;MRPL47;MRPL41;MRPL48;ICT1;MRPS22;MRPL52;MRPS26;MRPL55
Organelle biogenesis and maintenanceCLUAP1;C11orf60;MTERF;IFT80;MRPS33;DAP3;MKS1;TTC30A;UNC119B

MRPS31 has several biochemical functions, for example, poly(A) RNA binding, protein binding, protein domain specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS31 itself. We selected most functions MRPS31 had, and list some proteins which have the same functions with MRPS31. You can find most of the proteins on our site.

Function Related Protein
poly(A) RNA bindingZFP36L1;GNL3;PRDX1;RBM10;PKM;NME1;SLBP;RPS7;BCCIP
protein bindingTXNRD2;VPS18;IK;GSG2;LARS;SEMA7A;BCOR;PARVG;NANOS2
protein domain specific bindingHIST1H4K;WHRN;TJP2;STMN3;MRPL17;YWHAQ;CHMP2A;ZFP521;HAND2
structural constituent of ribosomeRPL31;RPL7L1;RPS9;MRPL27;RPS4Y2;MRPS16;RPS8;MRPS6;MRPS21

MRPS31 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS31 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS31.

STAT3; USP42; ITGB3BP; Brwd3; ssrna_ug; MAST3; ESR1; Rab5c; YBX1; Rad54l; MEX3C; SLX4; ESR2

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