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MSH4

Official Full Name

mutS homolog 4 (E. coli)
Overview

MutS protein homolog 4 is a protein that in humans is encoded by the MSH4 gene.
Synonyms

MSH4; mutS homolog 4 (E. coli); mutS protein homolog 4; MutS homolog 4 variant iota 1; MutS homolog 4 variant theta 1; mMsh4; AV144863; 4930485C04Rik;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MSH4-4119HCL	Recombinant Human MSH4 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MSH4-5651H	Recombinant Human MSH4 Protein, GST-tagged	Wheat Germ	GST		Inquiry

Involved Pathway
Protein Function
Interacting Protein
MSH4 Related Articles

MSH4 involved in several pathways and played different roles in them. We selected most pathways MSH4 participated on our site, such as Cell Cycle, Meiosis, Meiotic recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with MSH4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cell Cycle	NIPBL;GINS3;RAD21B;YWHAE;CDK5RAP2;TEX15;TFDP1;SMAD2;ARF1
Meiosis	FKBP6;TERF1;STAG2;TERF2IP;POT1;SYCP2;SPO11;SYNE1;ACD
Meiotic recombination	DMC1;MND1;MSH5;PSMC3IP;TEX15;SPO11;MSH4

MSH4 has several biochemical functions, for example, ATP binding, DNA binding, DNA-dependent ATPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MSH4 itself. We selected most functions MSH4 had, and list some proteins which have the same functions with MSH4. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	UBE2H;FKBP4;UPF1;SMARCAL1;TBK1;AARSD1;ACSL3;NMRK2;PRKCA
DNA binding	PUF60;HIST1H111R;EMX1;ZNF334;NKX2.4A;AIFM2;ZBTB6;IRF2A;PAX6A
DNA-dependent ATPase activity	IGHMBP2;CHD6;RAD51B;TOP2A;MSH3;SMARCAL1;RAD51C;MSH2;DMC1
NOT damaged DNA binding	MSH5;MSH4
mismatched DNA binding	MSH5;MSH4;PMS1;MSH6;MLH1;TDG;MLH3
protein binding	TMEM190;DBF4B;MAPK6;FBXO17;RNF220;HDGFRP2;PARVA;GFPT2;ADARB1

MSH4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSH4 here. Most of them are supplied by our site. Hope this information will be useful for your research of MSH4.

MSH5; EIF3F; ABL1

Namadurai, S; Jain, D; et al. The C-Terminal Domain of the MutL Homolog from Neisseria gonorrhoeae Forms an Inverted Homodimer. PLOS ONE 5:-(2010).

Douglas, JA; Gruber, SB; et al. History and molecular genetics of Lynch syndrome in family G - A century later. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 294:2195-2202(2005).