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MSI2

  • Official Full Name

    musashi homolog 2

  • Overview

    This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Two transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    MSI2; musashi homolog 2 (Drosophila); RNA-binding protein Musashi homolog 2; musashi-2; MSI2H; MGC3245; FLJ36569;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MSI2-225H Recombinant Human musashi RNA-binding protein 2, His-tagged E.coli His
Human MSI2-1115H Recombinant Human MSI2, GST-tagged E.coli GST 1-328aa
Human MSI2-4115HCL Recombinant Human MSI2 293 Cell Lysate HEK293 N/A
Human MSI2-5654H Recombinant Human MSI2 Protein, GST-tagged Wheat Germ GST
Human MSI2-4221H Recombinant Human MSI2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MSI2-1441H Recombinant Human MSI2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human MSI2-6562HF Recombinant Full Length Human MSI2 Protein, GST-tagged In Vitro Cell Free System GST 328 amino acids
Human MSI2-1441H-B Recombinant Human MSI2 Protein Pre-coupled Magnetic Beads HEK293
Human MSI2-386HFL Recombinant Full Length Human MSI2 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Msi2-4189M Recombinant Mouse Msi2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MSI2 Related Articles
  • MSI2 Related Research Area

MSI2 involved in several pathways and played different roles in them. We selected most pathways MSI2 participated on our site, such as mRNA surveillance pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MSI2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA surveillance pathwayNXT2;SMG6;PPP2R2BB;PCF11;CSTF2T;PPP1CA;MAGOH;MSI1;PPP1CBL

MSI2 has several biochemical functions, for example, nucleotide binding, poly(A) RNA binding, poly(U) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MSI2 itself. We selected most functions MSI2 had, and list some proteins which have the same functions with MSI2. You can find most of the proteins on our site.

Function Related Protein
nucleotide bindingC10orf28;HDGF;MAPK14A;GNAI2A;TNIKA;NSFA;RAF1B;HNRNPF;RBM39A
poly(A) RNA bindingPHF5A;YTHDF2;RBPMS;VSIG8;METTL16;TRMT6;PPIL4;SFRS9;DDX52
poly(U) RNA bindingPATL1;HNRNPC;DIS3L2;MSI1;PNPT1;MSI2;PATL2;KHDRBS1;HNRNPH1
protein bindingSEC16B;ENG;TH1L;POLR2J;LSM8;HP;PSMB7;PTPN22;TDRD9

MSI2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSI2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MSI2.

MEOX2; HNRNPH2; GRB2; SF1; pre-let-7a; CDK1; H2AFX; VCAM1; KIF21A

Gunter, KM; McLaughlin, EA; et al. Translational Control in Germ Cell Development: A Role for the RNA-Binding Proteins Musashi-1 and Musashi-2. IUBMB LIFE 63:678-685(2011).
Yokota, N; Mainprize, TG; et al. Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization. ONCOGENE 23:3444-3453(2004).
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