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MSL2

  • Official Full Name

    male-specific lethal 2 homolog

  • Synonyms

    MSL2; male-specific lethal 2 homolog (Drosophila); male specific lethal 2 like 1 (Drosophila) , MSL2L1, ring finger protein 184 , RNF184; male-specific lethal 2 homolog; FLJ10546; KIAA1585; male specific lethal 2 homolog (Drosophila); msl 2; MSL2-like 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Arabidopsis thaliana (Mouse-ear cress)
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MSL2-83H Recombinant Human MSL2, His-tagged E.coli His
Human MSL2-4114HCL Recombinant Human MSL2 293 Cell Lysate HEK293 N/A
Human MSL2-5656H Recombinant Human MSL2 Protein, GST-tagged Wheat Germ GST
Human MSL2-6459HF Recombinant Full Length Human MSL2 Protein, GST-tagged In Vitro Cell Free System GST 577 amino acids
Mouse MSL2-10138M Recombinant Mouse MSL2 Protein Mammalian Cell His
Mouse MSL2-5743M-B Recombinant Mouse MSL2 Protein Pre-coupled Magnetic Beads HEK293
Mouse MSL2-5743M Recombinant Mouse MSL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Arabidopsis thaliana (Mouse-ear cress) RFL34101AF Recombinant Full Length Arabidopsis Thaliana Mechanosensitive Ion Channel Protein 2, Chloroplastic(Msl2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (76-673)
Rhesus Macaque MSL2-2874R Recombinant Rhesus monkey MSL2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MSL2-2694R Recombinant Rhesus Macaque MSL2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MSL2-2694R-B Recombinant Rhesus Macaque MSL2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MSL2 Related Articles

MSL2 involved in several pathways and played different roles in them. We selected most pathways MSL2 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with MSL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesSMARCC1;PHF8;PBRM1;YEATS4;KAT6B;KIAA1267;KAT6A;SMARCB1;ZZZ3
Chromatin organizationC3orf75;SMARCA2;KDM5BB;SMARCC1B;PHF21A;EP400;MBD3A;ARID4A;KAT6B
HATs acetylate histonesATXN7L3;KAT7A;JADE1;EP400;KANSL2;TADA3;C3orf75;ZZZ3;ING5B

MSL2 has several biochemical functions, for example, ligase activity, ubiquitin protein ligase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MSL2 itself. We selected most functions MSL2 had, and list some proteins which have the same functions with MSL2. You can find most of the proteins on our site.

Function Related Protein
ligase activityRFWD3;TRIM32;MARCH9;UBE2IB;RNF5;MARCH11;RANBP2;TTLL6;UBE2KA
ubiquitin protein ligase activityRBBP6;ANAPC11;TRIM24;RNF144AA;MDM2;MED1;UBR5;TRAIP;PDZRN4
zinc ion bindingMMP13A;ENPP2;ATXN7L3;ZDHHC15A;SHPRH;ZFP622;MBD1B;CA9;CCNB1IP1

MSL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MSL2.

Kat8; YWHAG; YWHAE; q7ckv2_yerpe; aacA-aphD; TRIM8; WNK1; Mis12

Sugimoto, TN; Fujii, T; et al. Expression of a doublesex homologue is altered in sexual mosaics of Ostrinia scapulalis moths infected with Wolbachia. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 40:847-854(2010).
Abaza, I; Coll, O; et al. Drosophila UNR is required for translational repression of male-specific lethal 2 mRNA during regulation of X-chromosome dosage compensation. GENES & DEVELOPMENT 20:380-389(2006).
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