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MSX1

  • Official Full Name

    msh homeobox 1

  • Overview

    Msh homeobox 1 (Msx1) is a Muscle Segment Homeobox (Msh) gene family member that acts as a transcriptional repressor during embryonic development, playing an important role in limb pattern formation, craniofacial development, and tooth development. Msx1 i
  • Synonyms

    MSX1; msh homeobox 1; HOX7, msh (Drosophila) homeo box homolog 1 (formerly homeo box 7) , msh homeobox homolog 1 (Drosophila); homeobox protein MSX-1; HYD1; OFC5; homeobox 7; msh homeo box 1; homeobox protein Hox-7; msh homeobox homolog 1; msh homeobox;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MSX1-4105HCL Recombinant Human MSX1 293 Cell Lysate HEK293 N/A
Human MSX1-6476HF Recombinant Full Length Human MSX1 Protein, GST-tagged In Vitro Cell Free System GST 297 amino acids
Human MSX1-5676H Recombinant Human MSX1 Protein, GST-tagged Wheat Germ GST
Mouse MSX1-10154M Recombinant Mouse MSX1 Protein Mammalian Cell His
Mouse MSX1-5757M Recombinant Mouse MSX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Msx1-4199M Recombinant Mouse Msx1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MSX1-5757M-B Recombinant Mouse MSX1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque MSX1-2881R Recombinant Rhesus monkey MSX1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MSX1-2701R Recombinant Rhesus Macaque MSX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MSX1-2701R-B Recombinant Rhesus Macaque MSX1 Protein Pre-coupled Magnetic Beads HEK293
Chicken MSX1-7037C Recombinant Chicken MSX1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MSX1 Related Articles
  • MSX1 Related Research Area

MSX1 involved in several pathways and played different roles in them. We selected most pathways MSX1 participated on our site, such as HTLV-I infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with MSX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
HTLV-I infectionPIK3CB;CDC16;ANAPC7;NFATC3;PDGFB;NRP1;FDPS;EGR2;HLA-DMB

MSX1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, p53 binding, transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MSX1 itself. We selected most functions MSX1 had, and list some proteins which have the same functions with MSX1. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II regulatory region sequence-specific DNA bindingNHLH2;ZBTB16A;PHF21B;E2F7;PCGF6;AASS;CSDA;ZNF79;ZBTB12.2
p53 bindingBANP;SMARCA4;RNF34;ZNF385A;TAF3;SIRT1;CHD8;AXIN1;HTT
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific bindingDDN;SREBF1;HIST2H3A;SFPI1;RBPJL;ATF3;BATF2;FOSL1;TFAP2A
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingATF5;PKNOX1;CREB3L3;FEZF2;PAX9;CSRNP1;TRP53;STAG1;ETV5
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific bindingFEZF2;ETV7;ARHGAP35;PCGF6;ZBTB4;MNT;KLF12;NFKB1;MITF

MSX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MSX1.

MED19; NMNAT1; ING4; PTBP3

Sajan, SA; Rubenstein, JLR; et al. Identification of direct downstream targets of Dlx5 during early inner ear development. HUMAN MOLECULAR GENETICS 20:1262-1273(2011).
Houpis, CH; Tosios, KI; et al. Parathyroid hormone-related peptide (PTHrP), parathyroid hormone/parathyroid hormone-related peptide receptor 1 (PTHR1), and MSX1 protein are expressed in central and peripheral giant cell granulomas of the jaws. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY 109:415-424(2010).
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