MTMR14
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Official Full Name
myotubularin related protein 14
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Overview
This gene encodes a myotubularin-related protein. The encoded protein is a phosphoinositide phosphatase that specifically dephosphorylates phosphatidylinositol 3,5-biphosphate and phosphatidylinositol 3-phosphate. Mutations in this gene are correlated with autosomal dominant centronuclear myopathy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 18.[provided by RefSeq, Apr 2010] -
Synonyms
MTMR14; myotubularin related protein 14; C3orf29; myotubularin-related protein 14; jumpy; NS5ATP4ABP1; egg-derived tyrosine phosphatase homolog; HCV NS5A-transactivated protein 4 splice variant A-binding protein 1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- MTMR14 Related Articles
MTMR14 involved in several pathways and played different roles in them. We selected most pathways MTMR14 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | TPI1B;PLCZ1;PIP5K1AB;PTENB;INPPL1;ISYNA1;PLCD1B;INPP5KA;PI4K2A |
| Metabolic pathways | HMGCR;STT3A;GPAM;POLR2I;PGP;GUSB;NNT;PDHX;TPH1A |
| Phosphatidylinositol signaling system | PLCG1;PRKCG;MTM1;PLCB4;INPP4B;MTMR1B;PIP4K2C;ITPK1A;PIP5K1BB |
MTMR14 has several biochemical functions, for example, phosphatidylinositol-3-phosphatase activity, protein binding, protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR14 itself. We selected most functions MTMR14 had, and list some proteins which have the same functions with MTMR14. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-3-phosphatase activity | MTMR1B;MTMR1A;MTMR3;MTMR1;FIG4;MTM1;SACM1L;MTMR2;MTMR8 |
| protein binding | ECM1;PUM1;HNRNPM;C16orf5;PTPRD;LTBP1;AIFM1;SULT1A2;FH |
| protein tyrosine phosphatase activity | PTPRR;EYA3;MTMR14;CDC25C;PTPRU;SSH2B;TPTE;DUSP23A;DUSP18 |
MTMR14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTMR14 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTMR14.
TP53BP2; ENO3; Atg16l1; Atg12; MAP1LC3B
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