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MTRF1L

Official Full Name

mitochondrial translational release factor 1-like
Overview

Mitochondrial DNA encodes 13 proteins that play essential roles in the respiratory chain, while all proteins involved;in mitochondrial translation are encoded by nuclear genes that are imported from the cytoplasm. MTRF1L is a;nuclear-encoded protein that functions as a releasing factor that recognizes termination codons and releases;mitochondrial ribosomes from the synthesized protein (summary by Nozaki et al., 2008 (PubMed 18429816)).
Synonyms

MTRF1L; mitochondrial translational release factor 1-like; peptide chain release factor 1-like, mitochondrial; Mitochondrial translational release factor 1 like; mtRF1a; RF1ML_HUMAN; OTTHUMP00000017455; OTTHUMP00000017456; OTTHUMP00000017457; OTTHUMP00000017458; mitochondrial release factor 1 like; MRF1L; HMRF1L;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
MYC
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MTRF1L-1099H	Recombinant Human MTRF1L, His-tagged	E.coli	His	1-380aa	$319 / 25ug
Human	MTRF1L-4066HCL	Recombinant Human MTRF1L 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MTRF1L-6561HF	Recombinant Full Length Human MTRF1L Protein, GST-tagged	In Vitro Cell Free System	GST	271 amino acids	Inquiry
Human	MTRF1L-5734H	Recombinant Human MTRF1L Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	MTRF1L-10219M	Recombinant Mouse MTRF1L Protein	Mammalian Cell	His		Inquiry
Mouse	Mtrf1l-390M	Recombinant Mouse Mtrf1l Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Mouse	MTRF1L-5796M	Recombinant Mouse MTRF1L Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	MTRF1L-5796M-B	Recombinant Mouse MTRF1L Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	MTRF1L-3818R	Recombinant Rat MTRF1L Protein	Mammalian Cell	His		Inquiry
Rat	MTRF1L-3477R	Recombinant Rat MTRF1L Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MTRF1L-3477R-B	Recombinant Rat MTRF1L Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

MTRF1L involved in several pathways and played different roles in them. We selected most pathways MTRF1L participated on our site, such as Mitochondrial translation, Mitochondrial translation termination, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTRF1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPS35;MRPL48;GADD45GIP1;MRPS30;MRPS23;MTRF1L;MRPL42;GFM2;MRPS27
Mitochondrial translation termination	MRPS24;GFM2;MRPS36;MRPL55;MRPL37;MTRF1L;MRRF;MRPL47;MRPL46
Organelle biogenesis and maintenance	WDR19;TCTEX1D2;MRPL46;BBS10;IFT122;EXOC8;DYNLRB2;MRPL28;ARL13B

MTRF1L has several biochemical functions, for example, ribosome binding, translation release factor activity, codon specific. Some of the functions are cooperated with other proteins, some of the functions could acted by MTRF1L itself. We selected most functions MTRF1L had, and list some proteins which have the same functions with MTRF1L. You can find most of the proteins on our site.

Function	Related Protein
ribosome binding	MTRF1L;MTRF1;CPEB2;SEC61A1;SEC61B;RPSA;ETF1A;YTHDF1;NARG1
translation release factor activity, codon specific	MTRF1L;MTRF1;ETF1B;ETF1A;ETF1

MTRF1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTRF1L here. Most of them are supplied by our site. Hope this information will be useful for your research of MTRF1L.