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MTTP

  • Official Full Name

    microsomal triglyceride transfer protein

  • Overview

    MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008]
  • Synonyms

    MTTP; microsomal triglyceride transfer protein; ABL; MTP; microsomal triglyceride transfer protein large subunit; microsomal triglyceride transfer protein (large polypeptide, 88kDa);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MTTP-271H Recombinant Human MTTP Mammalian Cell His
Human MTTP-4064HCL Recombinant Human MTTP 293 Cell Lysate HEK293 N/A
Human MTTP-3541H Recombinant Human MTTP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human MTTP-5739H Recombinant Human MTTP Protein, GST-tagged Wheat Germ GST
Human MTTP-6566HF Recombinant Full Length Human MTTP Protein, GST-tagged In Vitro Cell Free System GST 151 amino acids
Human MTTP-3541H-B Recombinant Human MTTP Protein Pre-coupled Magnetic Beads HEK293
Mouse Mttp-7973M Recombinant Mouse Mttp protein, His & T7-tagged E.coli His/T7 Leu28~Gly459 (Accession # O08601)
Chicken MTTP-3761C Recombinant Chicken MTTP Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MTTP Related Articles

MTTP involved in several pathways and played different roles in them. We selected most pathways MTTP participated on our site, such as Fat digestion and absorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTTP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fat digestion and absorptionAGPAT2;SCARB1;SLC27A4;PLA2G2A;PNLIPRP1;PLA2G12A;CLPS;DGAT1;PPAP2A

MTTP has several biochemical functions, for example, lipid binding, lipid transporter activity, phospholipid transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTTP itself. We selected most functions MTTP had, and list some proteins which have the same functions with MTTP. You can find most of the proteins on our site.

Function Related Protein
lipid bindingPITPNM2;APOH;S1PR3;PTGS2;APOL6;PRAM1;MELK;FFAR1;PLEKHA2
lipid transporter activityAPOD;VTG1;APOA4;APOE;APOA2;VTG7;VTG6;MTTP;VTG2
phospholipid transporter activityABCA1;ABCA4;APOA1;ABCG1;MTTP;MFSD2A;MFSD2AB;ABCA13;OSBPL5
protein bindingDNAJB11;C5orf13;MYH9;MORN3;ZFPM2;C7orf53;MED29;TRIM37;CDCA8
protein heterodimerization activityPRSS28;CENPA;IRAK1;P4HB;MAP3K7;HIST4H4;HNF1A;THRA;HIST1H2BA

MTTP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTTP here. Most of them are supplied by our site. Hope this information will be useful for your research of MTTP.

Sahebkar, A; Chew, GT; et al. Recent advances in pharmacotherapy for hypertriglyceridemia. PROGRESS IN LIPID RESEARCH 56:47-66(2014).
Sahebkar, A; Watts, GF; et al. Managing recalcitrant hypercholesterolemia in patients on current best standard of care: efficacy and safety of novel pharmacotherapies. CLINICAL LIPIDOLOGY 9:221-233(2014).
  • Q&As
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