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MYF6

Official Full Name

myogenic factor 6 (herculin)
Overview

The protein encoded by this gene is a probable basic helix-loop-helix (bHLH) DNA binding protein involved in muscle differentiation. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM).
Synonyms

MYF6; myogenic factor 6 (herculin); myogenic factor 6; bHLHc4; MRF4; Class C basic helix-loop-helix protein 4; HERCULIN; Muscle-specific regulatory factor 4; Myf-6; MYF6_HUMAN; OTTHUMP00000243109;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MYF6-29361TH	Recombinant Human MYF6	Wheat Germ	N/A	99 amino acids	Inquiry
Human	MYF6-4033HCL	Recombinant Human MYF6 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MYF6-5801H	Recombinant Human MYF6 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MYF6-6741HF	Recombinant Full Length Human MYF6 Protein, GST-tagged	In Vitro Cell Free System	GST	242 amino acids	Inquiry
Mouse	MYF6-10297M	Recombinant Mouse MYF6 Protein	Mammalian Cell	His		Inquiry
Mouse	MYF6-5836M-B	Recombinant Mouse MYF6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	MYF6-5836M	Recombinant Mouse MYF6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MYF6-3844R	Recombinant Rat MYF6 Protein	Mammalian Cell	His		Inquiry
Rat	MYF6-3503R	Recombinant Rat MYF6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MYF6-3503R-B	Recombinant Rat MYF6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	MYF6-1181Z	Recombinant Zebrafish MYF6	Mammalian Cell	His		Inquiry
Chicken	MYF6-2447C	Recombinant Chicken MYF6	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MYF6 involved in several pathways and played different roles in them. We selected most pathways MYF6 participated on our site, such as C-MYB transcription factor network, CDO in myogenesis, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
C-MYB transcription factor network	ADA;SKI;TRIM28;MYC;MYOD1;ELANE;ADORA2B;COL1A2;PTCRA
CDO in myogenesis	CDH4;TCF3B;TCF12;CDON;BOC;MYOG;CTNNA2;MYOD1;TCF4
Developmental Biology	MED31;TDGF1;ARHGEF28;DUSP10;KBTBD7;EPHA10;CDK8;SPTA1;COL4A5
Diurnally regulated genes with circadian orthologs	G0S2;STBD1;CRY1;QKI;NR1D2;UCP3;MYF6;NCKAP1;CBX3
Id Signaling Pathway	IFI16;MYOD1;MYF6;ELK3;MSC;MYOG;ACVRL1;TCF3B;PAX2
Myogenesis	BOC;TCF4;CDON;TCF3B;MYOD1;MYF6;MEF2AA;TCF3A;MEF2B

MYF6 has several biochemical functions, for example, contributes_to E-box binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYF6 itself. We selected most functions MYF6 had, and list some proteins which have the same functions with MYF6. You can find most of the proteins on our site.

Function	Related Protein
contributes_to E-box binding	MYF5;MYF6;TCF3
RNA polymerase II core promoter proximal region sequence-specific DNA binding	AEBP2;STAT3;ZNF253;GATA1;POU4F3;AGO1;ZNF562;SNAI3;ELF4
protein heterodimerization activity	IKBKG;MAFG;BMP6;PPP2R4;ARNT2;CABYR;ATF1;MCL1A;H2-AB1
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	POU3F1;GATA6;SFPI1;PDX1;MEF2C;NFATC1;T;SOX7;ATF1
transcription factor activity, sequence-specific DNA binding	LCOR;HOMEZB;RARGB;ZNF691;TBR1B;POU6F2;NFIL3-5;ZSCAN20;HOXB4A
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	MAF;ONECUT3;FOXF1;SRF;BARHL2;MSGN1;TRP53;MAFB;MYF6

MYF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYF6.

LAMTOR5; TCF12