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MYH7B

Official Full Name

myosin, heavy chain 7B, cardiac muscle, beta
Overview

Myosins comprise a family of ATP-dependent motor proteins and are best known for their role in muscle contraction and their involvement in a wide range of other eukaryotic motility processes. They are responsible for actin-based motility. The term was originally used to describe a group of similar ATPases found in striated and smooth muscle cells. Following the discovery by Pollard and Korn of enzymes with myosin-like function in Acanthamoeba castellanii, a large number of divergent myosin genes have been discovered throughout eukaryotes. Thus, although myosin was originally thought to be restricted to muscle cells (hence, "myo"), there is no single "myosin" but rather a huge superfamily of genes whose protein products share the basic properties of actin binding, ATP hydrolysis (ATPase enzyme activity), and force transduction. Virtually all eukaryotic cells contain myosin isoforms. Some isoforms have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. The structure and function of myosin is strongly conserved across species, to the extent that rabbit muscle myosin II will bind to actin from an amoeba.
Synonyms

MYH7B; myosin, heavy chain 7B, cardiac muscle, beta; SM2, SSMHC; myosin heavy chain; myosin, heavy polypeptide 7B, cardiac muscle, beta; myosin-7B; slow myosin 2;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MYH7B-960H	Recombinant Human MYH7B	Mammalian Cell	His		Inquiry
Human	MYH7B-1481H	Recombinant Human MYH7B protein, His & GST-tagged	E.coli	His/GST	Asn829~Leu1106 (Accession # A7E2Y1)	Inquiry
Human	MYH7B-3557H	Recombinant Human MYH7B Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Human	MYH7B-3557H-B	Recombinant Human MYH7B Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	MYH7B-6156C	Recombinant Chicken MYH7B	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MYH7B involved in several pathways and played different roles in them. We selected most pathways MYH7B participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYH7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Tight junction	CLDN10A;MAGI2;ACTN3A;MPP5A;EPB41L1;ZAK;TJAP1;MYH11A;VMHCL

MYH7B has several biochemical functions, for example, ATP binding, actin binding, motor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYH7B itself. We selected most functions MYH7B had, and list some proteins which have the same functions with MYH7B. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	CDKL4;STK26;OPLAH;Adcy4;MAP2K5;TTLL3;PIK3CG;ATAD1;CDC34A
actin binding	HPCA;PDLIM5;ABLIM1B;TNNI1;DAG1;FLNC;PIP;EPS8L2;MYO19
motor activity	MYH9A;DYNC1I1;MYH7B;KIF3C;MYH11A;MYO1EB;DNAL4;DYNLT3;DNAHC8
protein binding	MMP9;PRKCB;NDUFS2;TMBIM6;TRIM41;PPM1F;STATH;PTK7;KAL1

MYH7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYH7B here. Most of them are supplied by our site. Hope this information will be useful for your research of MYH7B.

SMYD1; TNS2; SRRM1; b4e0q1_human; KPNA4; PDCD6; FXR1; NCBP2; CACNA2D1; RBBP5; MRPS27; ESR2; PGAM5; SEC62; POLDIP3; POLDIP3; COPS7B; BCLAF1