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MYL1

Official Full Name

myosin, light chain 1, alkali; skeletal, fast
Overview

Myosin light chain 3, skeletal muscle isoform is a protein that in humans is encoded by the MYL1 gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in fast skeletal muscle. Two transcript variants have been identified for this gene.
Synonyms

MYL1; myosin, light chain 1, alkali; skeletal, fast; myosin, light polypeptide 1, alkali; myosin light chain 1/3, skeletal muscle isoform; MLC1/MLC3; MLC1F/MLC3F; A1 catalytic; A2 catalytic; myosin light chain A1/A2; myosin light chain alk;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MYL1-29363TH	Recombinant Human MYL1	E.coli	N/A		Inquiry
Human	MYL1-4457H	Recombinant Human Myosin, Light Chain 1, His-tagged	E.coli	His		$298 / 100ug
Human	MYL1-1507H	Recombinant Human MYL1 protein, His-tagged	E.coli	His	Phe3~Ala142	Inquiry
Human	MYL1-4031HCL	Recombinant Human MYL1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MYL1-3261H	Recombinant Human MYL1 protein, GST-tagged	E.coli	GST	1-150aa	Inquiry
Human	MYL1-5806H	Recombinant Human MYL1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MYL1-6758HF	Recombinant Full Length Human MYL1 Protein, GST-tagged	In Vitro Cell Free System	GST	194 amino acids	Inquiry
Mouse	MYL1-10310M	Recombinant Mouse MYL1 Protein	Mammalian Cell	His		Inquiry
Mouse	MYL1-5843M-B	Recombinant Mouse MYL1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Myl1-4248M	Recombinant Mouse Myl1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	MYL1-5843M	Recombinant Mouse MYL1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	Myl1-1508R	Recombinant Rat Myl1 protein, His-tagged	E.coli	His	Phe3~Asn139 (Accession # P02600)	Inquiry
Rat	MYL1-3851R	Recombinant Rat MYL1 Protein	Mammalian Cell	His		Inquiry
Rat	MYL1-3510R	Recombinant Rat MYL1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MYL1-3510R-B	Recombinant Rat MYL1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	MYL1-10361Z	Recombinant Zebrafish MYL1	Mammalian Cell	His		Inquiry
Chicken	MYL1-3424C	Recombinant Chicken MYL1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MYL1 involved in several pathways and played different roles in them. We selected most pathways MYL1 participated on our site, such as Endothelin, G13 Signaling Pathway, Muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Endothelin	RAMP1;EDN1;EDNRA;EDNRB;CALCA;CALCRL;ECE1;MYL1;CNN1
G13 Signaling Pathway	SH3RF1;MYL1;GNA13;ARHGEF1A;CIT;DIAPH1;RHPN2;MYBPH;TNK2
Muscle contraction	MYBPC2;SORBS3;TMOD4;MYLZ3;SMYHC2;TNNI2A.3;TMEM8C;TNNI2;DMD
Regulation of Actin Cytoskeleton	HRASB;FGF10A;ITGB7;MYLK4;FGF10;MAP2K2A;ACTN3;FGD;IQGAP3
Striated Muscle Contraction	TCAP;TNNI2A.1;VIML;MYBPC2B;TNNI2B.1;TMOD3;MYL1;MYBPC3;TNNI2B.2

MYL1 has several biochemical functions, for example, calcium ion binding, structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by MYL1 itself. We selected most functions MYL1 had, and list some proteins which have the same functions with MYL1. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	C2CD4B;PCDHA8;MMP14B;ANXA5B;S100A8;NKD2B;PLCB2;DLB;GSNA
structural constituent of muscle	TPM1;MYOT;MYL6B;MYL6;SYNM;DMD;MYL3;TCAP;ASPH

MYL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYL1.

ANKRD1; LRRK2