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Mbl1

  • Official Full Name

    mannose-binding lectin (protein A) 1

  • Overview

    MBL belongs to the class of collectins in the C-type lectin superfamily, whose function appears to be pattern recognition in the first line of defense in the pre-immune host. MBL recognizes carbohydrate patterns, found on the surface of a large number of pathogenic micro-organisms, including bacteria, viruses, protozoa andfungi. Binding of MBL to a micro-organism results in activation of the lectin pathway of the complement system.Another important function of MBL is that this molecule binds senescent and apoptotic cells and enhances engulfment of whole, intact apoptotic cells, as well as cell debris by phagocytes.
  • Synonyms

    MBL1; mannose-binding lectin (protein A) 1; mannose-binding protein A; mannose binding lectin (A); MBP A; S MBP; raRF p28B; mannan-binding protein; mannose binding lectin, serum (A); ra-reactive factor polysaccharide-binding component p28B; MBL-A; MBP-A; S-MBP;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Mouse
  • Rat
  • Baculovirus-Insect cells
  • HEK293
  • Human Cell
  • Mammalian Cell
  • C
  • hFc
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse Mbl1-803M Recombinant Mouse Mbl1, His tagged Human Cell His
Mouse MBL1-2776MCL Recombinant Mouse MBL1 cell lysate Human Cell N/A
Mouse Mbl1-0145M Recombinant Mouse Mbl1 Protein (Ser18-Ala239), C-His-tagged Baculovirus-Insect cells C-His Ser18-Ala239
Rat Mbl1-20R Recombinant Rat Mbl1, Fc tagged Human Cell His
Rat MBL1-3602R Recombinant Rat MBL1 Protein Mammalian Cell His
Rat MBL1-1113RCL Recombinant Rat MBL1 cell lysate Human Cell N/A
Rat MBL1-3258R Recombinant Rat MBL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MBL1-1286R Recombinant Rat MBL1 protein(Met1-Ala238), hFc-tagged HEK293 C-hFc Met1-Ala238
Rat MBL1-3258R-B Recombinant Rat MBL1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Mbl1 Related Research Area

Mbl1 involved in several pathways and played different roles in them. We selected most pathways Mbl1 participated on our site, such as Phagosome, Complement and coagulation cascades, Staphylococcus aureus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with Mbl1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
PhagosomeTUBA1L2;BLB2;ITGB1B.2;HLA-DRB3;ATP6V0D1;C1R;HLA-F;H2-AB1;ITGA2
Complement and coagulation cascadesC3AR1;F13A1;KLKB1;C8G;PLAT;Serpina1b;C5AR1;CR1L;THBD
Staphylococcus aureus infectionFPR3;DSG1A;HLA-DRB4;C1R;FCGR3A;ITGAM;MASP1;ICAM1;HLA-DQA2

Mbl1 has several biochemical functions, for example, calcium ion binding, calcium-dependent protein binding, carbohydrate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Mbl1 itself. We selected most functions Mbl1 had, and list some proteins which have the same functions with Mbl1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingPCDH1G29;PCDHGA11;CAPN1A;THBS3A;PADI3;TPT1;PLCD1;CALM3;PCDHGB2
calcium-dependent protein bindingCCDC167;A2M;CHP;DMBT1;S100P;S100A11;ANXA2;SLC9A1;MBL1
carbohydrate bindingSIGLEC12;ILLR4;CLEC2G;PKD1;KLRC4-KLRK1;UAP1;FCN1;SIGLEC8;LMAN2
mannose bindingMAN2B1;DPM1;LMAN1;CLN5;CD209;M6PR;LMAN2L;MRC1;CD207
phosphatidylinositol-4-phosphate bindingMBL1;ARFIP2;SH3PXD2B;FAM21C;PLEKHA8;PLEKHF1;SNX24;D6WSU116E;JPH2
polysaccharide bindingCLEC18A;ENDOU;PRG4A;PRG4B;MBL1;VTN;CD209B;TINAGL1;CLEC18C
protease bindingSERPINA5;DERL1;NFRKB;LRP1;FURIN;NDUFS7;MALT1;LCN2;BRCA2
protein homodimerization activityGSTA4;AOC3;S100A16;MAP3K11;CISD2;MBL1;FLRT3;TAP1;GDNF

Mbl1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Mbl1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Mbl1.

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