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MPP1

  • Official Full Name

    membrane protein, palmitoylated 1, 55kDa

  • Overview

    This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    MPP1; membrane protein, palmitoylated 1, 55kDa; DXS552E, membrane protein, palmitoylated 1 (55kD); 55 kDa erythrocyte membrane protein; PEMP; palmitoylated 1; AAG 12; AAG12; Aging associated gene 12; DXS552; DXS552E; EM55_HUMAN; EMP 55; EMP55; Erythrocyte membrane protein p55; Membrane protein; Membrane protein palmitoylated 1 55kDa; Membrane protein palmitoylated 1; Migration related gene 1; MPP 1; MRG 1; MRG1; OTTHUMP00000026054; OTTHUMP00000196176; p55; Palmitoylated erythrocyte membrane protein; Palmitoylated membrane protein 1; aging-associated gene 12; migration-related gene 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MPP1-29357TH Recombinant Human MPP1, His-tagged E.coli His
Human MPP1-68H Recombinant Human MPP1 protein, His-tagged E.coli His 481aa(including fusion tag)
Human MPP1-4233HCL Recombinant Human MPP1 293 Cell Lysate HEK293 N/A
Human MPP1-6433H Recombinant Human MPP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human MPP1-6326HF Recombinant Full Length Human MPP1 Protein, GST-tagged In Vitro Cell Free System GST 466 amino acids
Human MPP1-2813H Recombinant Human MPP1 protein(11-280 aa), C-His-tagged E. coli C-His 11-280 aa
Human MPP1-5507H Recombinant Human MPP1 Protein, GST-tagged Wheat Germ GST
Mouse MPP1-9991M Recombinant Mouse MPP1 Protein Mammalian Cell His
Mouse MPP1-5652M-B Recombinant Mouse MPP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse MPP1-5652M Recombinant Mouse MPP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Mpp1-4124M Recombinant Mouse Mpp1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque MPP1-2814R Recombinant Rhesus monkey MPP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque MPP1-2634R Recombinant Rhesus Macaque MPP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque MPP1-2634R-B Recombinant Rhesus Macaque MPP1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish MPP1-12723Z Recombinant Zebrafish MPP1 Mammalian Cell His
Chicken MPP1-1796C Recombinant Chicken MPP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • MPP1 Related Articles

MPP1 involved in several pathways and played different roles in them. We selected most pathways MPP1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MPP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

MPP1 has several biochemical functions, for example, guanylate kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MPP1 itself. We selected most functions MPP1 had, and list some proteins which have the same functions with MPP1. You can find most of the proteins on our site.

Function Related Protein
guanylate kinase activityMPP1;DLG1L;DLG2;MPP3;GUK1B;DLG4;MPP2;DLG1;CARD11
protein bindingRAB7;BMPR1AA;RAB39A;LRCH3;NAPA;NMI;BUD13;COL4A3;SIAH1A

MPP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MPP1.

KLHL12; DNPEP; GYPC; OPTN; SGSM2; TK1; GADD45A; ATP5C1; GSK3B; NR1H2; STK3; RPS6KA1; SMN1; ZAK

Alahmad, A; Preuss, KD; et al. Desmoplakin and KIF20B as target antigens in patients with paroxysmal nocturnal haemoglobinuria. BRITISH JOURNAL OF HAEMATOLOGY 151:273-280(2010).
Berg, CP; Kannan, TR; et al. Mycoplasma antigens as a possible trigger for the induction of antimitochondrial antibodies in primary biliary cirrhosis. LIVER INTERNATIONAL 29:797-809(2009).
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