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Mks1

Official Full Name

Meckel Syndrome, Type 1
Overview

MAP Kinase substrate 1 (MKS1) is a protein from Arabidopsis that is phosphorylated by MAP Kinase 4 (MPK4). MPK4 has been shown to be involved in regulating plant defences against pathogens.
Synonyms

MKS1;Meckel syndrome, type 1;MES;MKS;BBS13;POC12;Meckel syndrome type 1 protein;FABB proteome-like protein;POC12 centriolar protein homolog;OTTHUMP00000165109;OTTHUMP00000165110;FLJ20345;OTTHUMP00000165111;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Zebrafish

Source

HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MKS1-5378H	Recombinant Human MKS1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	MKS1-6348HF	Recombinant Full Length Human MKS1 Protein, GST-tagged	In Vitro Cell Free System	GST	377 amino acids	Inquiry
Rat	MKS1-3698R	Recombinant Rat MKS1 Protein	Mammalian Cell	His		Inquiry
Rat	MKS1-3354R	Recombinant Rat MKS1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	MKS1-3354R-B	Recombinant Rat MKS1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	MKS1-4706Z	Recombinant Zebrafish MKS1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Mks1 involved in several pathways and played different roles in them. We selected most pathways Mks1 participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Hedgehog off state, which may be useful for your reference. Also, other proteins which involved in the same pathway with Mks1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Anchoring of the basal body to the plasma membrane	PCM1;CENPJ;CLASP1;CEP89;CEP135;CSNK1D;CEP63;CEP57;DYNC1H1
Assembly of the primary cilium	DYNC1H1;ATAT1;CP110;IFT43;TTC30A2;CEP63;TUBB4B;EXOC5;IFT27
Hedgehog off state	KIF7;MKS1;IFT88;KIF3A;IFT172;RPGRIP1L;TULP3;IFT122;IFT52
Hedgehog on state	EVC2;GPR161;CDON;SPOPL;EFCAB7;EVC;DZIP1;RPGRIP1L;BOC
Organelle biogenesis and maintenance	MKS1;LZTFL1;MRPS33;ARL3;DYF-1;TTC30A;MRPL46;MRPS27;AURKAIP1
Signal Transduction	PTGDR2;PDK3B;DCLRE1B;RGR;TLE2;PTHLH;KISS1;GPR120;SDR9C7
Signaling by Hedgehog	EVC2;GAS8;SPOPL;KIF7;IFT172;TTC21B;BOC;HHAT;IFT52

Mks1 has several biochemical functions, for example, molecular_function. Some of the functions are cooperated with other proteins, some of the functions could acted by Mks1 itself. We selected most functions Mks1 had, and list some proteins which have the same functions with Mks1. You can find most of the proteins on our site.

Function	Related Protein
molecular_function	GSDMC3;STOML3;CLEC12B;TTC36;ANK1A;DEFB121;GM13305;DSCR9;TDRD5

Mks1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Mks1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Mks1.