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NCAPD2

Official Full Name

non-SMC condensin I complex, subunit D2
Overview

CNAP1/hCAP-D2 is a regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condensed chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. It may target the condensin complex to DNA via its C-terminal domain (referenced from Swissprot).
Synonyms

NCAPD2; non-SMC condensin I complex, subunit D2; CNAP1; CAP-D2; hCAP-D2; condensin complex subunit 1; XCAP-D2 homolog; chromosome-associated protein D2; chromosome condensation related SMC associated protein 1; chromosome condensation-related SMC-associated protein 1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

HEK293
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	NCAPD2-1550H	Recombinant Human NCAPD2 Protein, GST-tagged	Wheat Germ	GST	Inquiry
Human	NCAPD2-372HCL	Recombinant Human NCAPD2 cell lysate		N/A	Inquiry
Mouse	NCAPD2-10456M	Recombinant Mouse NCAPD2 Protein	Mammalian Cell	His	Inquiry
Mouse	NCAPD2-5930M-B	Recombinant Mouse NCAPD2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	NCAPD2-5930M	Recombinant Mouse NCAPD2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Zebrafish	NCAPD2-7536Z	Recombinant Zebrafish NCAPD2	Mammalian Cell	His	Inquiry
Chicken	NCAPD2-3619C	Recombinant Chicken NCAPD2	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

NCAPD2 involved in several pathways and played different roles in them. We selected most pathways NCAPD2 participated on our site, such as Aurora B signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCAPD2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Aurora B signaling	KIF20A;SEPT1;NSUN2;NPM1;SGOL1;CBX5;TACC1;KIF2C;NDC80
Cell Cycle	CTDNEP1B;BRE;BUB3;SET;MDM2;TGFB1;YWHAQB;HTATIP;NCAPG
Cell Cycle, Mitotic	PHF8;NEDD1;ENSAA;MYCA;GINS3;NCAPG2;SKA2;GINS1;DYRK1A
Condensation of Prometaphase Chromosomes	NCAPG;NCAPH;SMC2;CSNK2B;SMC4;CSNK2A1;NCAPD2;CSNK2A2
M Phase	PMF1;MASTL;CDCA8;MIS12;MAU2;VRK2;CTDNEP1;MLF1IP;PDS5A
Mitotic Prometaphase	CENPO;MLF1IP;ZW10;ZWILCH;PMF1;CDCA5;SGOL2;CDCA8;PDS5B

NCAPD2 has several biochemical functions, for example, chromatin binding, histone binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCAPD2 itself. We selected most functions NCAPD2 had, and list some proteins which have the same functions with NCAPD2. You can find most of the proteins on our site.

Function	Related Protein
chromatin binding	NFIA;BAHD1;CCNT1;TOP1;ASCL1;KAT2A;PAF1;PPARG;BAHCC1
histone binding	L3MBTL1;RNF20;JAK2;DTX3L;NPM1;SET;SUPT6H;Ctsl;NCL
protein binding	GRIN2C;PHOSPHO2;SUV39H1;STX4;AP2M1;LMO3;MMP14;FRMD6;FMNL1

NCAPD2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCAPD2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCAPD2.

NCAPH; CSNK2A1; SMC2; NCAPG; NEK6; q8ck80_yerpe; SNW1; Ncaph; Smc4; CDC5L