NCAPG
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Official Full Name
non-SMC condensin I complex, subunit G
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Overview
This gene encodes a subunit of the condensin complex, which is responsible for the condensation and stabilization of;chromosomes during mitosis and meiosis. Phosphorylation of the encoded protein activates the condensin complex. There;are pseudogenes for this gene on chromosomes 8 and 15. Alternative splicing results in multiple transcript variants. -
Synonyms
NCAPG; non-SMC condensin I complex, subunit G; condensin complex subunit 3; CAP G; chromosome condensation protein G; FLJ12450; hCAP G; XCAP-G homolog; condensin subunit CAP-G; melanoma antigen NY-MEL-3; chromosome-associated protein G; CAPG; CHCG; HCAP-G;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NCAPG-4613H | Recombinant Human NCAPG Protein, GST-tagged | Wheat Germ | GST |
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| Zebrafish | NCAPG-8127Z | Recombinant Zebrafish NCAPG | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
NCAPG involved in several pathways and played different roles in them. We selected most pathways NCAPG participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Condensation of Prometaphase Chromosomes, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCAPG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell Cycle | HJURP;CCNE1;TBC1D8;CKS1B;NCAPG2;ENSA;CUL1B;SMARCA5;TP53BP1 |
| Cell Cycle, Mitotic | GMNN;CENPN;ODF2B;PDS5A;NEK9;GINS2;LEMD3;TUBGCP3;CDKN2A |
| Condensation of Prometaphase Chromosomes | SMC4;NCAPG;CSNK2A2;CSNK2A1;SMC2;NCAPD2;NCAPH;CSNK2B |
| M Phase | MCPH1;GOLGA2;CLIP1;ARPP19B;GORASP1;SPC24;SPC25;APITD1;WAPAL |
| Mitotic Prometaphase | ZW10;MIS12;CENPI;CENPL;ZWILCH;NDC80;CENPH;CCDC99;DSN1 |
NCAPG has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NCAPG itself. We selected most functions NCAPG had, and list some proteins which have the same functions with NCAPG. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
NCAPG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCAPG here. Most of them are supplied by our site. Hope this information will be useful for your research of NCAPG.
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, certain genetic variations in the NCAPG gene have been associated with altered protein expression and may influence disease susceptibility.
Studies suggest that high NCAPG expression may be associated with resistance to certain chemotherapy drugs, impacting treatment outcomes.
Techniques such as immunohistochemistry, western blotting, and ELISA are commonly used to quantify NCAPG protein levels in clinical samples.
Yes, there are diagnostic tests that can measure NCAPG protein levels in tissues and blood samples, which can aid in cancer diagnosis and prognosis.
Yes, there are ongoing clinical trials exploring the use of NCAPG-targeting agents in cancer treatment, evaluating their safety and efficacy.
Customer Reviews (3)
Write a reviewAs a researcher utilizing the NCAPG protein in my trials, I have experienced notable advantages that contribute to the efficiency and success of my research.
the NCAPG protein offers exceptional quality.
The manufacturer's responsive and knowledgeable support team is always available to answer my queries or provide guidance, ensuring that I can proceed with my research smoothly and without delays.
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