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NCBP1

  • Official Full Name

    nuclear cap binding protein subunit 1, 80kDa

  • Overview

    The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5 cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
  • Synonyms

    NCBP1; nuclear cap binding protein subunit 1, 80kDa; NCBP, nuclear cap binding protein subunit 1, 80kD; nuclear cap-binding protein subunit 1; CBP80; Sto1; NCBP 80 kDa subunit; 80 kDa nuclear cap-binding protein; NCBP; MGC2087;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Myc
  • DDK
  • Flag
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NCBP1-27855TH Recombinant Human NCBP1 Wheat Germ N/A 790 amino acids
Human NCBP1-29294TH Recombinant Human NCBP1 Wheat Germ N/A 98 amino acids
Human NCBP1-29240TH Recombinant Human NCBP1 Wheat Germ N/A 790 amino acids
Human NCBP1-1171HCL Recombinant Human NCBP1 cell lysate N/A
Human NCBP1-1228H Recombinant Human NCBP1 protein, His&Myc-tagged E.coli His&Myc 1-790aa
Human NCBP1-1356HFL Recombinant Full Length Human NCBP1 Protein, C-Flag-tagged Mammalian cells Flag
Human NCBP1-1290H Recombinant Human NCBP1 protein, His&Myc-tagged Insect Cell His&Myc 1-790aa
Human NCBP1-131H Recombinant Human NCBP1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human NCBP1-1484H Recombinant Human NCBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NCBP1-332HF Recombinant Full Length Human NCBP1 Protein In Vitro Cell Free System 790 amino acids
Human NCBP1-1484H-B Recombinant Human NCBP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse NCBP1-10462M Recombinant Mouse NCBP1 Protein Mammalian Cell His
Mouse NCBP1-5932M Recombinant Mouse NCBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ncbp1-4304M Recombinant Mouse Ncbp1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NCBP1-5932M-B Recombinant Mouse NCBP1 Protein Pre-coupled Magnetic Beads HEK293
Rat NCBP1-3917R Recombinant Rat NCBP1 Protein Mammalian Cell His
Rat NCBP1-3575R-B Recombinant Rat NCBP1 Protein Pre-coupled Magnetic Beads HEK293
Rat NCBP1-3575R Recombinant Rat NCBP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken NCBP1-3088C Recombinant Chicken NCBP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NCBP1 involved in several pathways and played different roles in them. We selected most pathways NCBP1 participated on our site, such as RNA transport, mRNA surveillance pathway, Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with NCBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportNXT2;EIF4E2RS1;NUP107;EEF1A1L2;THOC1;NUP133;POP7;FMR1;NUP205
mRNA surveillance pathwayPPP2R2B;NXT1;CPSF1;PABPC5;ALYREF;MAGOHB;PPP2R5B;WDR82;PPP2R2BB
SpliceosomeSRSF5;RBM8A;SR140;LSM5;U2AF1;EFTUD2;SRSF7;CDC40;SNW1

NCBP1 has several biochemical functions, for example, RNA binding, RNA cap binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCBP1 itself. We selected most functions NCBP1 had, and list some proteins which have the same functions with NCBP1. You can find most of the proteins on our site.

Function Related Protein
RNA bindingZBP1;SARNP;PKZ;IFIT8;RBM27;YTHDC1;ZFML;DDX19B;HNRNPC
RNA cap bindingNCBP1;EIF4E;EIF4G3;EIF4A1;SNUPN;EIF4E2;LARP1;NCBP2
poly(A) RNA bindingCHD2;REXO4;NOL12;HIST2H4A;GPATCH4;MKRN2;HMGN2;RPL27;SND1
protein bindingLEMD3;RPAP3;BCL10;DNAJA1;TNS4;DHX8;ID3;C4orf46;RBM4

NCBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCBP1.

NCBP2; RPS6; POLDIP3; PARN; EIF3B

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