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NCOA5

  • Official Full Name

    nuclear receptor coactivator 5

  • Overview

    This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this gene have been described. However, the full length nature of one of the variants has not been determined.
  • Synonyms

    NCOA5; nuclear receptor coactivator 5; bA465L10.6; CIA; coactivator independent of AF 2; MGC28864; KIAA1637; NCoA 5; OTTMUSP00000001057; RP23-61O3.13; NCoA-5; coactivator independent of AF-2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NCOA5-1215H Recombinant Human NCOA5, GST-tagged E.coli GST 112-384aa
Mouse NCOA5-10484M Recombinant Mouse NCOA5 Protein Mammalian Cell His
Mouse NCOA5-5947M-B Recombinant Mouse NCOA5 Protein Pre-coupled Magnetic Beads HEK293
Mouse NCOA5-5947M Recombinant Mouse NCOA5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NCOA5-2959R Recombinant Rhesus monkey NCOA5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NCOA5-2778R Recombinant Rhesus Macaque NCOA5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NCOA5-2778R-B Recombinant Rhesus Macaque NCOA5 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NCOA5-1309Z Recombinant Zebrafish NCOA5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NCOA5 Related Articles

NCOA5 involved in several pathways and played different roles in them. We selected most pathways NCOA5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NCOA5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

NCOA5 has several biochemical functions, for example, chromatin binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NCOA5 itself. We selected most functions NCOA5 had, and list some proteins which have the same functions with NCOA5. You can find most of the proteins on our site.

Function Related Protein
chromatin bindingHMGB3B;PRIMPOL;MNT;FABP1;ATXN7;TICRR;RELB;NCOA5;TOX4
poly(A) RNA bindingEIF4G2;PA2G4;SLTM;LBR;PPIL4;RPL7;RSRC2;MRPS24;RPL11
protein bindingCTIF;IFT172;FBXL8;OLIG3;COL18A1;PLAC9;EBF1;C21orf2;BARD1

NCOA5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NCOA5 here. Most of them are supplied by our site. Hope this information will be useful for your research of NCOA5.

Nr1d2; ESR1; TSC22D1; CDC37; cheY; AIM2; HNRNPA1; PPP1CC; MATR3; Fus; PPP1CB; PYHIN1; Srsf1; Taf15; PEO1; MPHOSPH8; MAP1LC3B; MAP1LC3A

Geier, A; Martin, IV; et al. Hepatocyte nuclear factor-4 alpha is a central transactivator of the mouse Ntcp gene. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 295:G226-G233(2008).
Liang, JJ; Wang, ZX; et al. The expression and function of androgen receptor coactivator p44 and protein arginine methyltransferase 5 in the developing testis and testicular tumors. JOURNAL OF UROLOGY 177:1918-1922(2007).
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