Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

NDC80

  • Official Full Name

    NDC80 kinetochore complex component

  • Overview

    This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]
  • Synonyms

    NDC80; NDC80 kinetochore complex component; HEC; HEC1; TID3; KNTC2; HsHec1; hsNDC80; kinetochore protein NDC80 homolog; kinetochore associated 2; kinetochore protein Hec1; kinetochore-associated protein 2; highly expressed in cancer protein; retinoblastoma-associated protein HEC; NDC80 kinetochore complex component homolog; NDC80 homolog, kinetochore complex component; highly expressed in cancer, rich in leucine heptad repeats;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NDC80-27986TH Recombinant Human NDC80, His-tagged E.coli His
Human NDC80-18H Recombinant Human NDC80 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NDC80-952HCL Recombinant Human NDC80 cell lysate N/A
Human NDC80-4899H Recombinant Human NDC80 Protein, GST-tagged Wheat Germ GST
Human NDC80-3898H Recombinant Human NDC80 Protein (Pro290-Glu642), N-His tagged E.coli N-His Pro290-Glu642
Human NDC80-3846H Recombinant Human NDC80 protein, His-tagged E.coli His 290-642 aa
Human NDC80-5981H Recombinant Human NDC80 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NDC80-2776HFL Recombinant Full Length Human NDC80 protein, Flag-tagged Mamanlian cells Flag
Mouse NDC80-10493M Recombinant Mouse NDC80 Protein Mammalian Cell His
Mouse NDC80-5949M-B Recombinant Mouse NDC80 Protein Pre-coupled Magnetic Beads HEK293
Mouse NDC80-5949M Recombinant Mouse NDC80 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey NDC80-730C Recombinant Cynomolgus NDC80 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey NDC80-474C Recombinant Cynomolgus Monkey NDC80 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey NDC80-474C-B Recombinant Cynomolgus Monkey NDC80 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque NDC80-2963R Recombinant Rhesus monkey NDC80 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NDC80-2782R Recombinant Rhesus Macaque NDC80 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NDC80-2782R-B Recombinant Rhesus Macaque NDC80 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NDC80-1150Z Recombinant Zebrafish NDC80 Mammalian Cell His
Chicken NDC80-6047C Recombinant Chicken NDC80 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NDC80 Related Articles

NDC80 involved in several pathways and played different roles in them. We selected most pathways NDC80 participated on our site, such as Aurora B signaling, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDC80 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Aurora B signalingSMC4;EVI5;INCENP;NCAPH;RACGAP1;SEPT1;AURKB;NDC80;DES
Cell CycleCLSPN;APITD1;PMF1;GINS4;GORASP1;BUB3;PTTG2;SMAD2;SMC1B
Cell Cycle, MitoticNCAPD3;MYBL2;TUBGCP2;TUBGCP3;CENPH;SPC25;DYRK1A;TUBG1;DCTN2
M PhaseSMC4;RANGAP1B;NIPBLA;ENSAB;MAU2;USO1;CENPC1;NEK7;NEK6
Mitotic AnaphaseDSN1;ZW10;SGOL2;VRK2;SPC25;ZWILCH;CDCA5;CENPC1;CENPP
Mitotic Metaphase and AnaphaseNUDC;MLF1IP;NUF2;CENPE;KNTC1;CCDC99;ANKLE2;RCC2;VRK2
Mitotic PrometaphaseCENPP;PDS5B;SKA1;CENPL;CENPQ;PDS5A;SGOL2;NDEL1A;NCAPH
PLK1 signaling eventsPLK1S1;NDC80;TPT1;ERCC6L;SPC24;BORA;ECT2;TCTN2;TPX2

NDC80 has several biochemical functions, for example, identical protein binding, protein binding, structural constituent of cytoskeleton. Some of the functions are cooperated with other proteins, some of the functions could acted by NDC80 itself. We selected most functions NDC80 had, and list some proteins which have the same functions with NDC80. You can find most of the proteins on our site.

Function Related Protein
identical protein bindingKHDRBS1;MAP1S;MRI1;CLDND;FBXW7;TPRGL;SNX8;ASMT;AKT1
protein bindingMYD88;TNFAIP8L2;ZCCHC17;C6orf226;BANK1;SIN3A;TIMP1;GATA6;AIPL1
structural constituent of cytoskeletonKRT71;TUBA1L2;KRT15;ACTG1;ACTL7A;ACTL7B;INA;KRT5;SORBS3

NDC80 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDC80 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDC80.

NUF2; ZWINT

Boeckmann, L; Takahashi, Y; et al. Phosphorylation of centromeric histone H3 variant regulates chromosome segregation in Saccharomyces cerevisiae. MOLECULAR BIOLOGY OF THE CELL 24:2034-2044(2013).
Sun, SC; Zhang, DX; et al. Ndc80 Regulates Meiotic Spindle Organization, Chromosome Alignment, and Cell Cycle Progression in Mouse Oocytes. MICROSCOPY AND MICROANALYSIS 17:431-439(2011).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All NDC80 Products

Required fields are marked with *

My Review for All NDC80 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends