NDUFAF4
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
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Overview
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency. -
Synonyms
NDUFAF4; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4; C6orf66, chromosome 6 open reading frame 66; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; bA22L21.1; HRPAP20; HSPC125; My013; C6orf66; Hormone-regulated proliferation-associated protein of 20 kDa; NDUF4_HUMAN; hormone-regulated proliferation-associated protein, 20 kDa;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- NDUFAF4 Related Articles
NDUFAF4 involved in several pathways and played different roles in them. We selected most pathways NDUFAF4 participated on our site, such as Metabolism, Respiratory electron transport, Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins., which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFAF4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Metabolism | ACY3;UST;CBLC-1;AKAP5;GLIPR1;YY2;SULT2ST1;CKM;IVD |
Respiratory electron transport | NDUFAF2;NDUFAF4;TIMMDC1;ETFDH;ETFA;NDUFAF7;SCO1;SURF1;C2orf56 |
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | ETFB;SURF1;NDUFAF2;ATP5L;NDUFAF3;UCP2;UCP3;COX16;SCO1 |
The citric acid (TCA) cycle and respiratory electron transport | NDUFAF3;NDUFAF4;ADHFE1;ATP5S;COX16;TACO1;MPC1;NDUFAF2;SLC25A27 |
NDUFAF4 has several biochemical functions, for example, calmodulin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFAF4 itself. We selected most functions NDUFAF4 had, and list some proteins which have the same functions with NDUFAF4. You can find most of the proteins on our site.
Function | Related Protein |
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calmodulin binding | CALD1B;DCX;ADD2;UPF3B;CAMK1GB;TRPV5;ORAI1;ADCY1;CAMK1G |
protein binding | SPN;OLIG1;ACLY;ASB3;ALS2;STX4;GRN;Tnfrsf23;UBLCP1 |
NDUFAF4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFAF4 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFAF4.
NDUFAF3; NDUFAF3; NDUFS5; NDUFS7; P; TIMMDC1; NDUFA13
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