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NDUFS7

  • Official Full Name

    NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)

  • Overview

    This gene encodes a protein that is a subunit of one of the complexes that forms the mitochondrial respiratory chain.;This protein is one of over 40 subunits found in complex I, the nicotinamide adenine dinucleotide (NADH):ubiquinone;oxidoreductase. This complex functions in the transfer of electrons from NADH to the respiratory chain, and ubiquinone;is believed to be the immediate electron acceptor for the enzyme. Mutations in this gene cause Leigh syndrome due to;mitochondrial complex I deficiency, a severe neurological disorder that results in bilaterally symmetrical necrotic;lesions in subcortical brain regions.
  • Synonyms

    NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase); NADH dehydrogenase (ubiquinone) Fe S protein 7 (20kD) (NADH coenzyme Q reductase); CI 20; complex I 20kDa subunit; FLJ45860; FLJ46880; NADH dehydrogenase [ubiquinon;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NDUFS7-562H Recombinant Human NDUFS7 Mammalian Cell His
Human NDUFS7-3893HCL Recombinant Human NDUFS7 293 Cell Lysate HEK293 N/A
Human NDUFS7-3607H Recombinant Human NDUFS7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NDUFS7-3607H-B Recombinant Human NDUFS7 Protein Pre-coupled Magnetic Beads HEK293
Mouse NDUFS7-10547M Recombinant Mouse NDUFS7 Protein Mammalian Cell His
Mouse NDUFS7-5993M-B Recombinant Mouse NDUFS7 Protein Pre-coupled Magnetic Beads HEK293
Mouse NDUFS7-5993M Recombinant Mouse NDUFS7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish NDUFS7-7890Z Recombinant Zebrafish NDUFS7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NDUFS7 involved in several pathways and played different roles in them. We selected most pathways NDUFS7 participated on our site, such as Alzheimers disease, Electron Transport Chain, Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFS7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Alzheimers diseaseNAE1;GRIN2A;PPP3R2;APBB1;NDUFB3;ERN1;NDUFA7;FADD;RYR3
Electron Transport ChainCOX6A1;SLC25A14;COX11;COX8A;COX6B1;SLC25A27;COX6C;NDUFC2-KCTD14;COX7C
Huntingtons diseaseNDUFB11;DCTN2;COX7B2;SDHA;NDUFC2-KCTD14;PPARG;NDUFB7;DNALC1;SOD2
Metabolic pathwaysATP6V1B2;NDUFA1;ATP6V1C1;NOS3;MLYCD;SPTLC1;B3GNT2B;KYNU;HAO1
MetabolismADA;HELZ2;PTGR1;AK8;AKR1C21;INSIG1;CDS1;ALDH9A1A.2;DLAT
Non-alcoholic fatty liver disease (NAFLD)NDUFA12;NDUFA6;INS1;FASLG;PIK3R1;DDIT3;BAX;NDUFB8;NDUFB11
Oxidative phosphorylationUQCR11;Atp5g2;ATP4A;ATPV0E2;ATP6V1H;NDUFA1;ATP6V1BA;ATP12A;ATP6V1E1
Parkinsons diseaseAPAF1;DRD1A;NDUFA1;NDUFC2-KCTD14;MT-ND4;ATP5C1;MT-ND1;UQCRC1;NDUFA2

NDUFS7 has several biochemical functions, for example, 4 iron, 4 sulfur cluster binding, NADH dehydrogenase (ubiquinone) activity, contributes_to NADH dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFS7 itself. We selected most functions NDUFS7 had, and list some proteins which have the same functions with NDUFS7. You can find most of the proteins on our site.

Function Related Protein
4 iron, 4 sulfur cluster bindingNDUFS1;NUBP1;NUBP2;MOCS1;POLA1;MUTYH;ISCA2;NDUFV1;ISCU
NADH dehydrogenase (ubiquinone) activityNDUFA4;NDUFA12;NDUFA10;NDUFC1;NDUFS6;NDUFA9;NDUFA5;NDUFB7;NDUFA1
contributes_to NADH dehydrogenase activityNDUFV1;NDUFS8;NDUFS7;NDUFS2
metal ion bindingRTEL1;CHPT1;POLL;ZFP42;ASAP2B;ZSCAN4;DMRTB1;DTX1;KLF6A
oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptorAKR1C3;DCXR;AKR1C6;CBR1;AKR1C4;AKR1C21;AKR1C2;DHRS4;NDUFS7
protease bindingCasp3;TRP53;RYR1;PEO1;SERPINA5;BDKRB2;KIT;F3;SERPINA1D
protein bindingCD3E;PPP1R12C;GSG1L;ANXA11;AP1M1;LSM7;CDK5;GPR19;BANK1
quinone bindingNDUFS2;AMOTL1;AOC2;VKORC1;SQRDL;TP53I3;AOC3;ETFDH;ABP1

NDUFS7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFS7 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFS7.

NDUFA2; ENO2; ARRB2; NDUFS8; NDUFS5; NDUFS2; NDUFS3; SCO1; ETHE1; NQO1; NDUFS1; LONP1; NDUFA6; ALDH6A1; NDUFA5; NDUFA9; NDUFAF5

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