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NEK9

  • Official Full Name

    NIMA (never in mitosis gene a)- related kinase 9

  • Overview

    Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression.
  • Synonyms

    NEK9; NIMA (never in mitosis gene a)- related kinase 9; serine/threonine-protein kinase Nek9; DKFZp434D0935; MGC16714; Nek8; NERCC; nercc1 kinase; nimA-related kinase 8; NIMA-related kinase Nek8; nimA-related protein kinase 9; never in mitosis A-related k;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Sf21
  • Sf9 Insect Cell
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NEK9-1064H Active Recombinant Human NEK9, GST-tagged Sf9 Insect Cell GST 1-979; deleted fragment of 346-731
Human NEK9-1064 Active Recombinant Human NEK9 protein, GST-tagged Insect Cell GST 1-979; deleted fragment of 346-731
Human NEK9-175H Active Recombinant Human NEK9(1-324) Protein, N-His-tagged Sf21 His 1-324 aa
Human NEK9-1259H Recombinant Human NEK9, GST-tagged E.coli GST C-term-345aa
Human NEK9-66H Recombinant Human NEK9 protein, Flag-tagged, Biotinylated Insect Cell Flag
Human NEK9-3876HCL Recombinant Human NEK9 293 Cell Lysate HEK293 N/A
Human NEK9-2902H Recombinant Human NEK9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NEK9-0835H Recombinant Human NEK9 Protein (S2-L979), GST tagged Insect Cell GST S2-L979
Human NEK9-0834H Recombinant Human NEK9 Protein (S2-L979), Tag Free Insect Cell No tag S2-L979
Mouse Nek9-4370M Recombinant Mouse Nek9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque NEK9-3000R Recombinant Rhesus monkey NEK9 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NEK9-2819R Recombinant Rhesus Macaque NEK9 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NEK9-2819R-B Recombinant Rhesus Macaque NEK9 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NEK9 involved in several pathways and played different roles in them. We selected most pathways NEK9 participated on our site, such as Activation of NIMA Kinases NEK9, NEK6, NEK7, Cell Cycle, Cell Cycle, Mitotic, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEK9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Activation of NIMA Kinases NEK9, NEK6, NEK7NEK9;NEK6;NEK7
Cell CycleGINS3;SGOL1;CDK7;TGFB1A;MCM6;SMC1AL;GADD45AB;CCNE1;AKAP9
Cell Cycle, MitoticBANF1;NCAPD2;ENSAA;NEK6;SGOL1;DSN1;NUMA1;NCAPH2;CSNK2A1
M PhaseCENPL;INCENP;PDS5A;PHF8;NCAPD2;NIPBLA;GOLGA2;ZW10;CENPO
Mitotic ProphaseCNEP1R1;NEK6;GORASP2;SMC2;VRK2;ARPP19A;CTDNEP1;SET;CTDNEP1A
Nuclear Envelope BreakdownNEK6;CTDNEP1B;CTDNEP1A;TMEM188;CNEP1R1;CTDNEP1;DULLARD;NEK7;NEK9
Nuclear Pore Complex (NPC) DisassemblyNEK6;NEK9;NEK7

NEK9 has several biochemical functions, for example, ATP binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEK9 itself. We selected most functions NEK9 had, and list some proteins which have the same functions with NEK9. You can find most of the proteins on our site.

Function Related Protein
ATP bindingHSP90AA1.1;HSPA5;ZRANB3;MVD;TDRD12;HSPA8;EIF4A3;PANK3;CDKL4
metal ion bindingLHX1A;AMPD3;GMEB2;NRXN3B;ELAC2;ZNF213;PRKCZ;ZBTB26;INO80B
protein bindingNEK11;MAP3K14;HSPA1B;PPP6R2;SRA1;SCP2;MYO18A;INCA1;SNRNP27
protein kinase bindingPPP1R12A;PPP1CB;KIF14;CDKN2D;BAG5;RPTOR;SHC1;VRK1;AGAP2
protein serine/threonine kinase activityGRK1B;SLC14A2;MARK2;PRKCBA;ARAF;MAP2K2A;CSNK1E;CAMK1DA;GSK3A

NEK9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEK9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEK9.

GABARAPL2; DYNLL1; PLK1; GABARAPL1

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