NET1
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Official Full Name
neuroepithelial cell transforming 1
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Overview
Neuroepithelial cell-transforming gene 1 protein is a protein that in humans is encoded by the NET1 gene. -
Synonyms
NET1; neuroepithelial cell transforming 1; neuroepithelial cell-transforming gene 1 protein; ARHGEF8; NET1A; proto-oncogene p65 Net1; p65 Net1 proto-oncogene protein; small GTP-binding protein regulator; neuroepithelioma transforming gene 1; neuroepitheli;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NET1-562H | Recombinant Human NET1 Protein, His-tagged | E.coli | His |
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| Human | NET1-3873HCL | Recombinant Human NET1 293 Cell Lysate | HEK293 | N/A |
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| Human | NET1-4586H | Recombinant Human NET1 protein, His-SUMO-tagged | E.coli | His-SUMO | 1-542aa |
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| Zebrafish | NET1-1843Z | Recombinant Zebrafish NET1 | Mammalian Cell | His |
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| Chicken | NET1-2355C | Recombinant Chicken NET1 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
NET1 involved in several pathways and played different roles in them. We selected most pathways NET1 participated on our site, such as Cell death signalling via NRAGE, NRIF and NADE, G alpha (12/13) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with NET1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell death signalling via NRAGE, NRIF and NADE | BCL2L11;ARHGEF17;CASP2;DCLRE1B;ECT2;OBSCN;ITSN1;AKAP13;ARHGEF16 |
| G alpha (12/13) signalling events | MCF2L;FGD4;DCLRE1B;ARHGAP4A;ITSN1;ECT2;ARHGEF16;ARHGEF18;OBSCN |
| GPCR downstream signaling | GRP;PYYA;KALRN;CCR9;ADORA2A;CCL19A.2;NPB;SSTR4;DGKA |
| NRAGE signals death through JNK | ARHGEF17;ARHGEF9;ABR;PLEKHG2;FGD2;ECT2;MCF2L;ARHGAP4A;ARHGEF18 |
| Regulation of RhoA activity | AKAP13;DEF6;ARHGEF18;ARHGEF28;DLC1;NET1;ARHGAP4;ABR;ARHGEF3 |
| Rho GTPase cycle | ARHGAP4A;GDI2;ARHGAP12B;ARHGAP4;ARHGEF18;FGD2;FAM13B;ARHGEF18A;ARHGAP9 |
| Signal Transduction | SCT;RPGRIP1L;PAG1;PMEPA1;CCNT2A;FSTL3;ADH8A;AMOTL2A;SOX7 |
| Signaling by GPCR | PTH;GPR18;PROK2;RGS18;ARHGEF17;VIP2;OR10A5;RAMP3;GPR39 |
NET1 has several biochemical functions, for example, GTP-Rho binding, Rho guanyl-nucleotide exchange factor activity, guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NET1 itself. We selected most functions NET1 had, and list some proteins which have the same functions with NET1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GTP-Rho binding | ROCK2B;CDC42EP1B;TNFAIP1;ROCK2A;TRIOBP;WHAMM;CDC42EP4;CDC42EP5;PKN1 |
| Rho guanyl-nucleotide exchange factor activity | BCR;ARHGEF3L;MCF2L;OBSCN;ARHGEF12;ARHGEF1B;ARHGEF7;RASGRF2;DOCK9 |
| guanyl-nucleotide exchange factor activity | RIC8;RASGEF1BA;FNIP1;SH2D3CB;FARP2;RASGEF1C;FGD4;SH2D3A;VAV2 |
NET1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NET1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NET1.
PRKAB2; USP11
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