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NHLH1

Official Full Name

nescient helix loop helix 1
Overview

The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).
Synonyms

NHLH1; nescient helix loop helix 1; HEN1; helix-loop-helix protein 1; bHLHa35; NSCL; NSCL1; Class A basic helix-loop-helix protein 35; HEN-1; HEN1_HUMAN; NSCL-1; OTTHUMP00000031860;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NHLH1-29924TH	Recombinant Human NHLH1	Wheat Germ	N/A	133 amino acids	Inquiry
Human	NHLH1-246H	Recombinant Human nescient helix loop helix 1, His-tagged	E.coli	His		Inquiry
Human	NHLH1-13735H	Recombinant Human NHLH1, GST-tagged	E.coli	GST	1-114a.a.	$319 / 25ug
Human	NHLH1-3833HCL	Recombinant Human NHLH1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NHLH1-340HF	Recombinant Full Length Human NHLH1 Protein	In Vitro Cell Free System		133 amino acids	Inquiry
Human	NHLH1-2430H	Recombinant Human NHLH1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	NHLH1-10648M	Recombinant Mouse NHLH1 Protein	Mammalian Cell	His		Inquiry
Mouse	NHLH1-6054M-B	Recombinant Mouse NHLH1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Nhlh1-4412M	Recombinant Mouse Nhlh1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	NHLH1-6054M	Recombinant Mouse NHLH1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Chicken	NHLH1-5697C	Recombinant Chicken NHLH1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
NHLH1 Related Articles

NHLH1 involved in several pathways and played different roles in them. We selected most pathways NHLH1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NHLH1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NHLH1 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein dimerization activity, transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NHLH1 itself. We selected most functions NHLH1 had, and list some proteins which have the same functions with NHLH1. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II regulatory region sequence-specific DNA binding	AEBP1;PRDM12B;CGGBP1;ZNF561;HOXD9;FOXC1;EOMES;ATF5A;AIRE
protein dimerization activity	MYCLA;NEUROD4;MYO5A;AHRRB;STK3;ARNTL;MXD3;ARNTL1B;DERL3
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	BARHL2;HSF2;OVOL2;SOHLH1;NKX2;ELF5;NHLH1;CSRNP2;ALX1

NHLH1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NHLH1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NHLH1.

HIVEP1; INO80E; PSME2

Ratie, L; Ware, M; et al. Dynamic expression of Notch-dependent neurogenic markers in the chick embryonic nervous system. FRONTIERS IN NEUROANATOMY 8:-(2014).

Chen, C; Zhang, CL; et al. Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia. BIPOLAR DISORDERS 16:790-799(2014).