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NKD1

Official Full Name

naked cuticle homolog 1 (Drosophila)
Overview

In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.
Synonyms

NKD1; naked cuticle homolog 1 (Drosophila); protein naked cuticle homolog 1; Dvl-binding protein; naked cuticle 1 homolog; Naked-1; NKD; naked cuticle-1; Naked1;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	NKD1-860H	Recombinant Human NKD1	Mammalian Cell	His	Inquiry
Human	NKD1-3627H	Recombinant Human NKD1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Human	NKD1-3627H-B	Recombinant Human NKD1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	NKD1-3851Z	Recombinant Zebrafish NKD1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

NKD1 involved in several pathways and played different roles in them. We selected most pathways NKD1 participated on our site, such as Wnt signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NKD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Wnt signaling pathway	DAAM1;FZD3;RHOAC;FBXW11;PORCNL;TP53;PPARD;GSK3AA;MAPK8A
Hippo signaling pathway	AMH;WNT16;PPP2R1A;TCF7L2;TEAD1;SMAD1;FZD8;YWHAG;ID1

NKD1 has several biochemical functions, for example, PDZ domain binding, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKD1 itself. We selected most functions NKD1 had, and list some proteins which have the same functions with NKD1. You can find most of the proteins on our site.

Function	Related Protein
PDZ domain binding	ATP2B1B;GRIA1;PSEN1;CFTR;LIN7C;DTNA;ARHGAP29;ACOX1;FZD2
calcium ion binding	ANXA4;CALR3B;CLSTN1;ANXA1;NOX5;S100A10A;PKD2L2;NOTCH3;NCALDB
protein binding	BRK1;ZNF18;TBCD;OCIAD1;NTRK3;GCA;NUCB2;NRP1;TAC1

NKD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKD1.

PPP2R3A; PPP2R3A; PPP2R1A; PPP2CA; Dvl1