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NKX2-2

Official Full Name

NK2 homeobox 2
Overview

Homeobox protein Nkx-2.2 is a protein that in humans is encoded by the NKX2-2 gene. Homeobox protein Nkx-2.2 contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Synonyms

Nkx2.2; NKX2-2; NKX2.2; NKX2B; NK2 homeobox 2;

Type

Recombinant Proteins

Species

Chicken
Human
Mouse

Source

E.coli
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His|SUMO

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NKX2-2-332H	Recombinant Human NKX2-2 Protein, His-tagged	E.coli	His		Inquiry
Human	NKX2-2-1303H	Recombinant Human NKX2-2, GST-tagged	E.coli	GST	1-129aa	$319 / 25ug
Human	NKX2-2-3805H	Recombinant Human NKX2-2 protein, His-tagged	E.coli	His	1-129 aa	$319 / 25ug
Human	NKX2-2-6676HF	Recombinant Full Length Human NKX2-2 Protein, GST-tagged	In Vitro Cell Free System	GST	273 amino acids	Inquiry
Human	NKX2-2-5896H	Recombinant Human NKX2-2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Mouse	NKX2-2-1766M	Recombinant Mouse NKX2-2 Protein (1-273 aa), His-SUMO-tagged	E.coli	His/SUMO	1-273 aa	Inquiry
Chicken	NKX2-2-5090C	Recombinant Chicken NKX2-2	Mammalian Cell	His		Inquiry

NKX2-2 Related Articles
NKX2-2 Related Research Area

NKX2-2 involved in several pathways and played different roles in them. We selected most pathways NKX2-2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX2-2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NKX2-2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NKX2-2 itself. We selected most functions NKX2-2 had, and list some proteins which have the same functions with NKX2-2. You can find most of the proteins on our site.

Function	Related Protein

NKX2-2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX2-2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX2-2.

Shibuya, R; Matsuyama, A; et al. The combination of CD99 and NKX2.2, a transcriptional target of EWSR1-FLI1, is highly specific for the diagnosis of Ewing sarcoma. VIRCHOWS ARCHIV 465:599-605(2014).

Clark, JK; O'keefe, A; et al. Mammalian Nkx2.2(+) Perineurial Glia Are Essential for Motor Nerve Development. DEVELOPMENTAL DYNAMICS 243:1116-1129(2014).

Glioma Biomarkers

Pancreatic Endoderm Cell Markers

Neural Stem Cell Transcription Factors

Endodermal Lineage Markers