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NKX2-3

Official Full Name

NK2 transcription factor related, locus 3 (Drosophila)
Overview

This gene encodes a homeodomain-containing transcription factor. The encoded protein is a member of the NKX family of homeodomain transcription factors. Studies of similar proteins in mouse and rat have indicated a potential role in cellular differentiat
Synonyms

NKX2-3; NK2 transcription factor related, locus 3 (Drosophila); homeobox protein Nkx-2.3; Homeobox protein NK-2 homolog C; homeobox protein NKX2-3 homolog; MGC127415; NK-2 (Drosophila) homolog C; NK2 transcription factor homolog C; NK2 transcription factor related, locus 3; NK2.3; NKX2.3; NKX23; NKX2C; tinman; nkx2-C; homeobox protein NK-2 homolog 3; Drosophila NK2 transcription factor related, locus 3; Nkx-2.3;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NKX2-3-5898H	Recombinant Human NKX2-3 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	NKX2-3-6678HF	Recombinant Full Length Human NKX2-3 Protein, GST-tagged	In Vitro Cell Free System	GST	293 amino acids	Inquiry
Human	NKX2-3-301372H	Recombinant Human NKX2-3 protein, GST-tagged	E.coli	GST	Asn19-Arg148	Inquiry
Mouse	NKX2-3-10699M	Recombinant Mouse NKX2-3 Protein	Mammalian Cell	His		Inquiry
Mouse	NKX2-3-6084M	Recombinant Mouse NKX2-3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	NKX2-3-6084M-B	Recombinant Mouse NKX2-3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	NKX2-3-6588C	Recombinant Chicken NKX2-3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
NKX2-3 Related Articles

NKX2-3 involved in several pathways and played different roles in them. We selected most pathways NKX2-3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX2-3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NKX2-3 has several biochemical functions, for example, DNA binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKX2-3 itself. We selected most functions NKX2-3 had, and list some proteins which have the same functions with NKX2-3. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ZFP516;ZFP28;GM14482;ZNF547;PROX1A;PRDM13;ZFP239;ATXN1L;HIST2H2L
sequence-specific DNA binding	GSX2;ETV5A;RHOXF1;PBX1A;CSRNP3;HOXA13A;FOXF1;NKX6.2;GATA2A

NKX2-3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX2-3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX2-3.

Plevy, S; Silverberg, MS; et al. Combined Serological, Genetic, and Inflammatory Markers Differentiate Non-IBD, Crohn's Disease, and Ulcerative Colitis Patients. INFLAMMATORY BOWEL DISEASES 19:1139-1148(2013).

Kellermayer, Z; Labadi, A; et al. Absence of Nkx2-3 Homeodomain Transcription Factor Induces the Formation of LYVE-1-Positive Endothelial Cysts without Lymphatic Commitment in the Spleen. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 59:690-700(2011).