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NLN

  • Official Full Name

    neurolysin (metallopeptidase M3 family)

  • Overview

    This gene encodes a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
  • Synonyms

    NLN; neurolysin (metallopeptidase M3 family); AGTBP, angiotensin binding protein; neurolysin, mitochondrial; KIAA1226; endopeptidase 24.16; microsomal endopeptidase; neurotensin endopeptidase; angiotensin binding protein; angiotensin-binding protein; mit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NLN-5693H Active Recombinant Human Neurolysin (metallopeptidase M3 family), His-tagged E.coli His
Human NLN-348H Recombinant Human NLN, His-tagged E.coli His Ser38-Pro704
Human NLN-1061H Recombinant Human NLN Mammalian Cell His
Human NLN-3806HCL Recombinant Human NLN 293 Cell Lysate HEK293 N/A
Human NLN-5918H Recombinant Human NLN Protein, GST-tagged Wheat Germ GST
Human NLN-327H Recombinant Human NLN Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human NLN-6717HF Recombinant Full Length Human NLN Protein, GST-tagged In Vitro Cell Free System GST 704 amino acids
Human NLN-1282HFL Recombinant Full Length Human NLN Protein, C-Flag-tagged Mammalian cells Flag
Human NLN-1516H Recombinant Human NLN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NLN-1516H-B Recombinant Human NLN Protein Pre-coupled Magnetic Beads HEK293
Mouse NLN-10712M Recombinant Mouse NLN Protein Mammalian Cell His
Mouse Nln-4433M Recombinant Mouse Nln Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NLN-6092M Recombinant Mouse NLN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NLN-6092M-B Recombinant Mouse NLN Protein Pre-coupled Magnetic Beads HEK293
Rat NLN-3999R Recombinant Rat NLN Protein Mammalian Cell His
Rat NLN-3658R Recombinant Rat NLN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat NLN-3658R-B Recombinant Rat NLN Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NLN Related Articles

NLN involved in several pathways and played different roles in them. We selected most pathways NLN participated on our site, such as Renin-angiotensin system, which may be useful for your reference. Also, other proteins which involved in the same pathway with NLN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Renin-angiotensin systemKLK1B11;AGTR1A;ANPEP;KLK1;REN2;AGTR1B;THOP1;KLK1B9;PREP

NLN has several biochemical functions, for example, metal ion binding, metalloendopeptidase activity, peptide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NLN itself. We selected most functions NLN had, and list some proteins which have the same functions with NLN. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingCNOT4B;ZFP687;PDCD2;JAZF1A;ITGA4;ZFC3H1;PHYHD1;XGB;KDM2AA
metalloendopeptidase activityECEL1;ADAMTS8;ADAM5P;MEP1A.1;ADAMTS20;MMP8;MEP1A;ADAMTS3;ADAM17A
peptide bindingCTSB;ERAP2;ADNP;OXTRL;FNTB;GPR22;GNRHR;PLOD1;AVPR2L

NLN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLN here. Most of them are supplied by our site. Hope this information will be useful for your research of NLN.

Dicer1; NCAPD3; DYNLL1; CBX1; HIF1A; Tnks2; Naa11; Eea1; RASSF8; ZNF526; RUFY1; MRPL9; Calml3; Fign; KLC4; GAR1; Cetn2

El-Ghonaimy, EA; El-Shinawi, M; et al. Positive lymph-node breast cancer patients - activation of NF-kappa B in tumor-associated leukocytes stimulates cytokine secretion that promotes metastasis via C-C chemokine receptor CCR7. FEBS Journal 282:271-282(2015).
Antunes, SLG; Chimelli, L; et al. Histopathological examination of nerve samples from pure neural leprosy patients: obtaining maximum information to improve diagnostic efficiency. MEMORIAS DO INSTITUTO OSWALDO CRUZ 107:246-253(2012).
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