Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

NLRP6

Official Full Name

NLR family, pyrin domain containing 6
Overview

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs,;such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a;NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636),;also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD).;NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in;multiprotein complexes called inflammasomes (Tschopp et al., 2003 (PubMed 12563287)).
Synonyms

NLRP6; NLR family, pyrin domain containing 6; NACHT, LRR and PYD domains-containing protein 6; CLR11.4; NACHT, leucine rich repeat and PYD containing 6; NACHT, LRR and PYD containing protein 6; NALP6_HUMAN; Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 6; PAN3; PYPAF5; PYRIN containing APAF1 like protein 5; PYRIN-containing APAF1-like protein 5; angiotensin; angiotensin II/vasopressin receptor; dual angiotensin II/vasopressin receptor; Nalp6;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Rat
Rhesus Macaque

Source

HEK293
Insect Cell
Mammalian Cell

Tag

His
His (Fc)
Avi
MBP
No tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NLRP6-0069H	Recombinant Human NLRP6 Protein (M1-F892), Tag Free	Insect Cell	No tag	M1-F892	Inquiry
Human	NLRP6-0070H	Recombinant Human NLRP6 Protein (M1-F892), His/MBP tagged	Insect Cell	His/MBP	M1-F892	Inquiry
Rat	NLRP6-4000R	Recombinant Rat NLRP6 Protein	Mammalian Cell	His		Inquiry
Rat	NLRP6-3659R	Recombinant Rat NLRP6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	NLRP6-3659R-B	Recombinant Rat NLRP6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	NLRP6-3049R	Recombinant Rhesus monkey NLRP6 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	NLRP6-2868R-B	Recombinant Rhesus Macaque NLRP6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	NLRP6-2868R	Recombinant Rhesus Macaque NLRP6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

NLRP6 involved in several pathways and played different roles in them. We selected most pathways NLRP6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NLRP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NLRP6 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NLRP6 itself. We selected most functions NLRP6 had, and list some proteins which have the same functions with NLRP6. You can find most of the proteins on our site.

Function	Related Protein

NLRP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NLRP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NLRP6.