NMD3
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Official Full Name
NMD3 homolog
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Overview
Ribosomes are composed of 60S and 40S subunits that are assembled in the nucleolus and exported to the cytoplasm;through nuclear pore complexes in the nuclear envelope. NMD3 is an adaptor for 60S subunit export via the CRM1 (XPO1;;MIM 602559) pathway (Trotta et al., 2003 (PubMed 12773398)). -
Synonyms
NMD3; NMD3 homolog (S. cerevisiae); 60S ribosomal export protein NMD3; CGI 07; hNMD3; CGI-07; FLJ21053;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- NMD3 Related Articles
NMD3 involved in several pathways and played different roles in them. We selected most pathways NMD3 participated on our site, such as Ribosome biogenesis in eukaryotes, RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | XRN2;NOP56;POP4;GNL3L;WDR75;CIRH1A;DKC1;NVL;UTP14A |
| RNA transport | NXF1;EIF3A;PAIP1;SNUPN;THOC6;THOC4;EIF2B1;EIF3HA;PABPC1A |
NMD3 has several biochemical functions, for example, poly(A) RNA binding, protein binding, bridging, ribosomal large subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NMD3 itself. We selected most functions NMD3 had, and list some proteins which have the same functions with NMD3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| poly(A) RNA binding | GRB2;LARP1;PTCD2;EIF4A2;PRPF40A;NOM1;AKAP17A;CPSF7;VSIG8 |
| protein binding, bridging | PSMC6;PPP4R2;FLRT2;FSCN3;RAD50;TIRAP;FBXW7;NEFL;EVPL |
| ribosomal large subunit binding | EIF6;MRRF;MALSU1;CPEB2;NPM1;RBM3;OLA1;NMD3 |
NMD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NMD3.
CSNK2A1; OTUD4; SLX4
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