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NMNAT1

  • Official Full Name

    nicotinamide nucleotide adenylyltransferase 1

  • Overview

    This gene encodes an enzyme which catalyzes a key step in the biosynthesis of the coenzyme NAD. The encoded protein is one of several nicotinamide nucleotide adenylyltransferases. Studies in Drosophila and mammalian neurons have shown the encoded protein can confer protection to damaged neurons. This protection requires enzymatic activity which increases NAD levels and activates a nuclear deacetylase which is the protective molecule. Pseudogenes of this gene are located on chromosomes 1, 3, 4, 14 and 15. [provided by RefSeq, Dec 2011]
  • Synonyms

    NMNAT1; nicotinamide nucleotide adenylyltransferase 1; LCA9; NMNAT; PNAT1; nicotinamide mononucleotide adenylyltransferase 1; NMN adenylyltransferase 1; NaMN adenylyltransferase 1; Lebers congenital amaurosis 9; pyridine nucleotide adenylyltransferase 1; nicotinate-nucleotide adenylyltransferase 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf21 Insect Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NMNAT1-29821TH Active Recombinant Human NMNAT1 protein, His-tagged E.coli His
Human NMNAT1-25H Active Recombinant Human NMNAT1, His-tagged Sf21 Insect Cell His
Human NMNAT1-26H Active Recombinant Human NMNAT1, His-tagged E.coli His
Human NMNAT1-77H Active Recombinant Human NMNAT1 protein, His-tagged Insect Cell His
Human NMNAT1-544H Recombinant Human NMNAT1, His tagged Insect Cell His
Human NMNAT1-1316H Recombinant Human NMNAT1, GST-tagged E.coli GST 1-279aa
Human NMNAT1-2766H Recombinant Human NMNAT1, His-tagged E.coli His
Human NMNAT1-001HCL Recombinant Human NMNAT1 cell lysate Insect Cell N/A
Human NMNAT1-5937H Recombinant Human NMNAT1 Protein, GST-tagged Wheat Germ GST
Human NMNAT1-1163H Recombinant Human NMNAT1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NMNAT1-6280H Recombinant Human NMNAT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NMNAT1-6593HF Recombinant Full Length Human NMNAT1 Protein, GST-tagged In Vitro Cell Free System GST 279 amino acids
Human NMNAT1-2171HFL Recombinant Full Length Human NMNAT1 Protein, C-Flag-tagged Mammalian cells Flag
Human NMNAT1-1520H Recombinant Human NMNAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NMNAT1-1520H-B Recombinant Human NMNAT1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Nmnat1-4443M Recombinant Mouse Nmnat1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish NMNAT1-2400Z Recombinant Zebrafish NMNAT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NMNAT1 involved in several pathways and played different roles in them. We selected most pathways NMNAT1 participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMNAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Nicotinate and nicotinamide metabolismPNP5A;NT5M;NMRK2;CD38;AOX3;AOX3L1;MIBP2;NADKB;NADKD1
Metabolic pathwaysMTMR8;DGAT1;LPCAT1;SGMS2;NDUFB3;RFK;CYP11B2;GLULA;GALCA

NMNAT1 has several biochemical functions, for example, ATP binding, nicotinamide-nucleotide adenylyltransferase activity, nicotinate-nucleotide adenylyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NMNAT1 itself. We selected most functions NMNAT1 had, and list some proteins which have the same functions with NMNAT1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTMEM38A;PRKCQ;MCCC1;IGF1RA;MYO1A;DAPK1;ABCB5;ACSF3;ATP5A1
nicotinamide-nucleotide adenylyltransferase activityNMNAT1;NMNAT2;NMNAT3
nicotinate-nucleotide adenylyltransferase activityABL1;NMNAT2;NMNAT3;NMNAT1
protein bindingMDM2;PCDH17;ATXN10;NARG1;BAI3;KPNA3;APC2;ZNF524;JAM3B

NMNAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMNAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NMNAT1.

SIRT1; CCNC; KPNA2; MSX1; NEK3; SIK1; FLOT2; NTRK2; Espl1; Osgep; Spire2; Dctn3

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