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NMNAT3

  • Official Full Name

    nicotinamide nucleotide adenylyltransferase 3

  • Overview

    This gene encodes a member of the nicotinamide/nicotinic acid mononucleotide adenylyltransferase family. These enzymes use ATP to catalyze the synthesis of nicotinamide adenine dinucleotide or nicotinic acid adenine dinucleotide from nicotinamide mononucleotide or nicotinic acid mononucleotide, respectively. The encoded protein is localized to mitochondria and may also play a neuroprotective role as a molecular chaperone. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms

    NMNAT3; nicotinamide nucleotide adenylyltransferase 3; nicotinamide mononucleotide adenylyltransferase 3; PNAT3; NaMN adenylyltransferase 3; Nicotinate-nucleotide adenylyltransferase 3; NMN adenylyltransferase 3; NMNA3_HUMAN; NMNAT 3; PNAT 3; PNAT-3; Pyridine nucleotide adenylyltransferase 3; FKSG76;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NMNAT3-639H Recombinant Human NMNAT3, His-tagged E.coli His
Human NMNAT3-1201HCL Recombinant Human NMNAT3 cell lysate N/A
Human NMNAT3-4679H Recombinant Human NMNAT3 protein, His-SUMO-tagged E.coli His-SUMO 1-215aa
Human NMNAT3-5942H Recombinant Human NMNAT3 Protein, GST-tagged Wheat Germ GST
Human NMNAT3-6597HF Recombinant Full Length Human NMNAT3 Protein, GST-tagged In Vitro Cell Free System GST 215 amino acids
Mouse NMNAT3-10749M Recombinant Mouse NMNAT3 Protein Mammalian Cell His
Mouse NMNAT3-6115M-B Recombinant Mouse NMNAT3 Protein Pre-coupled Magnetic Beads HEK293
Mouse NMNAT3-6115M Recombinant Mouse NMNAT3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NMNAT3 Related Articles

NMNAT3 involved in several pathways and played different roles in them. We selected most pathways NMNAT3 participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMNAT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Nicotinate and nicotinamide metabolismNT5C1B;NT5C1B-RDH14;NT5M;NT5C2;NMRK1;CD38;NADK2;NAPRT1;ITGB1BP3
Metabolic pathwaysGCDHA;ARG2;FAM213B;LASS4;PLCD4;URAD;GPAA1;MINPP1;TREH

NMNAT3 has several biochemical functions, for example, ATP binding, nicotinamide-nucleotide adenylyltransferase activity, nicotinate-nucleotide adenylyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NMNAT3 itself. We selected most functions NMNAT3 had, and list some proteins which have the same functions with NMNAT3. You can find most of the proteins on our site.

Function Related Protein
ATP bindingCLK4;RIOK2;TNIKB;TEC;ACVR1C;MYO1A;ATAD2;MYO5A;DALRD3
nicotinamide-nucleotide adenylyltransferase activityNMNAT3;NMNAT1;NMNAT2
nicotinate-nucleotide adenylyltransferase activityNMNAT2;NMNAT1;ABL1;NMNAT3

NMNAT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMNAT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NMNAT3.

Knepper, A; Schleicher, M; et al. Enhancement of the NAD(P)(H) pool in Saccharomyces cerevisiae. ENGINEERING IN LIFE SCIENCES 8:381-389(2008).
Franchetti, P; Pasqualini, M; et al. Stereoselective synthesis of nicotinamide beta-riboside and nucleoside analogs. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 14:4655-4658(2004).
  • Q&As
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