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NMUR2

Official Full Name

neuromedin U receptor 2
Overview

This gene encodes a protein from the G-protein coupled receptor 1 family. This protein is a receptor for neuromedin U, which is a neuropeptide that is widely distributed in the gut and central nervous system. This receptor plays an important role in the regulation of food intake and body weight.
Synonyms

NMUR2; neuromedin U receptor 2; NMU2R; neuromedin-U receptor 2; G-protein coupled receptor FM-4; G-protein coupled receptor TGR-1; growth hormone secretagogue receptor family, member 4; FM4; FM-4; TGR1; TGR-1; NMU-R2;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Bos taurus (Bovine)
Homo sapiens (Human)
Human
Mouse
Mus musculus (Mouse)
Rat
Rattus norvegicus (Rat)

Source

E.coli expression system
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NMUR2-3780HCL	Recombinant Human NMUR2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NMUR2-5950H	Recombinant Human NMUR2 Protein	Wheat Germ	N/A		Inquiry
Human	NMUR2-6614HF	Recombinant Full Length Human NMUR2 Protein	In Vitro Cell Free System		2,002 amino acids	Inquiry
Human	NMUR2-5951H	Recombinant Human NMUR2 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	NMUR2-6664HF	Recombinant Full Length Human NMUR2 Protein, GST-tagged	In Vitro Cell Free System	GST	415 amino acids	Inquiry
Mouse	NMUR2-10757M	Recombinant Mouse NMUR2 Protein	Mammalian Cell	His		Inquiry
Mouse	NMUR2-6123M	Recombinant Mouse NMUR2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	NMUR2-6123M-B	Recombinant Mouse NMUR2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	NMUR2-4012R	Recombinant Rat NMUR2 Protein	Mammalian Cell	His		Inquiry
Rat	NMUR2-3671R	Recombinant Rat NMUR2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	NMUR2-3671R-B	Recombinant Rat NMUR2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Bos taurus (Bovine)	RFL30209BF	Recombinant Full Length Bovine Neuromedin-U Receptor 2(Nmur2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-407)	Inquiry
Homo sapiens (Human)	RFL12847HF	Recombinant Full Length Human Neuromedin-U Receptor 2(Nmur2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-415)	Inquiry
Mus musculus (Mouse)	RFL14765MF	Recombinant Full Length Mouse Neuromedin-U Receptor 2(Nmur2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-395)	Inquiry
Rattus norvegicus (Rat)	RFL2733RF	Recombinant Full Length Rat Neuromedin-U Receptor 2(Nmur2) Protein, His-Tagged	E.coli expression system	His	Full Length (1-395)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
NMUR2 Related Articles
NMUR2 Related Research Area

NMUR2 involved in several pathways and played different roles in them. We selected most pathways NMUR2 participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with NMUR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Neuroactive ligand-receptor interaction	GRM5;TRHR;GRM1;TAAR11;GRM2A;MLNR;TAAR8C;CHRNB3A;MTNR1BB

NMUR2 has several biochemical functions, for example, G-protein coupled receptor activity, GTP binding, intracellular calcium activated chloride channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NMUR2 itself. We selected most functions NMUR2 had, and list some proteins which have the same functions with NMUR2. You can find most of the proteins on our site.

Function	Related Protein
G-protein coupled receptor activity	GPR182;PTGDR2;TAAR7F;HTR2CL1;RRH;GRM6;APLNRB;CALCRL;GPR128
GTP binding	ARL15A;GNA15.4;GNA12A;EEF2B;TUBA8;ARL16;RAB32A;MXA;RHOGB
intracellular calcium activated chloride channel activity	ANO4;ANO7;ANO8;CLCA1;ANO6;ANO2;NMUR2;CLCA2;CLCA4
neuromedin U binding
neuromedin U receptor activity	NMUR2;NMUR1
protein binding	CREB3;KRTAP10-5;NR5A1;PLSCR4;ATM;EPC1;RBBP4;MYLIP;TRIM22

NMUR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NMUR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of NMUR2.

TCF4; TRAF2; ADAMTSL4; NOTCH2NL

Chen, RX; Liu, F; et al. Neuromedin S Increases L-type Ca2+ Channel Currents Through G(i)alpha-protein and Phospholipase C-dependent Novel Protein Kinase C Delta Pathway in Adult Rat Ventricular Myocytes. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY 30:618-630(2012).

Zhang, YA; Jiang, DS; et al. Activation of neuromedin U type 1 receptor inhibits L-type Ca2+ channel currents via phosphatidylinositol 3-kinase-dependent protein kinase C epsilon pathway in mouse hippocampal neurons. CELLULAR SIGNALLING 22:1660-1668(2010).

Neurotransmitter G Protein-Coupled Receptors