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NNMT

  • Official Full Name

    nicotinamide N-methyltransferase

  • Overview

    N-methylation is one method by which drug and other xenobiotic compounds are metabolized by the liver. This gene encodes the protein responsible for this enzymatic activity which uses S-adenosyl methionine as the methyl donor.
  • Synonyms

    NNMT; nicotinamide N-methyltransferase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Human
  • Mouse
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Insect Cell
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • His|SUMO
  • Myc|DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NNMT-193H Active Recombinant Human NNMT protein, GST-tagged Insect Cell GST
Human NNMT-148H Active Recombinant Human NNMT protein, His-tagged E.coli His
Human NNMT-143H Recombinant Human Nicotinamide N-methyltransferase, His-tagged E.coli His
Human NNMT-149H Recombinant Human NNMT protein, His/SUMO-tagged E.coli His/SUMO
Human NNMT-1320H Recombinant Human NNMT, GST-tagged E.coli GST 1-264aa
Human NNMT-134H Recombinant Human NNMT Protein, GST-tagged E.coli GST 2-264
Human NNMT-27994TH Recombinant Human NNMT, T7 -tagged E.coli T7
Human NNMT-218H Recombinant Human NNMT protein, His-tagged E.coli His
Human NNMT-27992TH Recombinant Human NNMT, His-tagged E.coli His
Human NNMT-452H Recombinant Human NNMT protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NNMT-3779HCL Recombinant Human NNMT 293 Cell Lysate HEK293 N/A
Human NNMT-185H Recombinant Human NNMT Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human NNMT-780H Recombinant Human NNMT Protein, His-tagged E.coli His Met1~Arg258
Human NNMT-234H Active Recombinant Human NNMT Protein, His-tagged, Bioactivity Validated E.coli His 1-264aa
Human NNMT-5956H Recombinant Human NNMT Protein, GST-tagged Wheat Germ GST
Human NNMT-2158HFL Recombinant Full Length Human NNMT protein, Flag-tagged Mamanlian cells Flag
Human NNMT-034H Recombinant Human NNMT Protein, His/SUMO-tagged E. coli His/SUMO
Human NNMT-017H Recombinant Human NNMT Protein, His/SUMO-tagged E.coli His/SUMO
Human NNMT-6669HF Recombinant Full Length Human NNMT Protein, GST-tagged In Vitro Cell Free System GST 264 amino acids
Human NNMT-4714H Recombinant Human NNMT Protein (Met1-Arg258), His tagged E.coli His Met1-Arg258
Mouse NNMT-10759M Recombinant Mouse NNMT Protein Mammalian Cell His
Mouse Nnmt-781M Recombinant Mouse Nnmt Protein, His-tagged E.coli His Met1~Glu264
Mouse Nnmt-4449M Recombinant Mouse Nnmt Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse NNMT-6125M Recombinant Mouse NNMT Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NNMT-6125M-B Recombinant Mouse NNMT Protein Pre-coupled Magnetic Beads HEK293
Kit-2215 N'-Nicotinamide Methyltransferase (NNMT) Inhibitor Screening Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NNMT Related Research Area

NNMT involved in several pathways and played different roles in them. We selected most pathways NNMT participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with NNMT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Nicotinate and nicotinamide metabolismNAMPTB;NT5C2B;AOX3L1;QPRT;KCNG4;NMRK2;PNP6;PNP;NT5C
Metabolic pathwaysCKB;GCNT2;MVD;TWISTNB;ALDH6A1;NT5E;ANPEPB;AGXTA;PLA2G6

NNMT has several biochemical functions, for example, nicotinamide N-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NNMT itself. We selected most functions NNMT had, and list some proteins which have the same functions with NNMT. You can find most of the proteins on our site.

Function Related Protein
nicotinamide N-methyltransferase activity

NNMT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NNMT here. Most of them are supplied by our site. Hope this information will be useful for your research of NNMT.

ATF6; BMF

  • Q&As
  • Reviews

Q&As (5)

Ask a question
Can NNMT protein be used as a biomarker for diseases? 04/18/2023

Yes, elevated levels of NNMT in blood or tissues have been proposed as potential biomarkers for certain diseases.

How does NNMT affect cardiovascular health? 07/01/2022

Elevated NNMT levels have been associated with increased risk of cardiovascular diseases, making it a potential therapeutic target.

Are there any drugs targeting NNMT protein? 08/15/2019

Research is ongoing to develop drugs that modulate NNMT activity as potential treatments for diseases where NNMT is implicated.

How is NNMT protein clinically relevant? 04/11/2017

NNMT has been linked to several diseases and health conditions, making it a potential target for therapeutic interventions.

What diseases are associated with NNMT dysfunction? 06/10/2016

NNMT dysregulation has been associated with metabolic disorders, cancer, neurodegenerative diseases, and cardiovascular diseases.

Customer Reviews (3)

Write a review
Reviews
01/22/2021

    Its high specificity and functional integrity ensure accurate and reproducible data, allowing researchers to draw meaningful conclusions from their experiments.

    11/10/2018

      This protein is known for its exceptional quality and purity, providing reliable and consistent results.

      01/25/2017

        The NNMT protein offers numerous advantages in trials and research experiments, making it an excellent choice for researchers.

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