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NOC2L

Official Full Name

nucleolar complex associated 2 homolog
Overview

Histone modification by histone acetyltransferases (HAT) and histone deacetylases (HDAC) can control major aspects of;transcriptional regulation. NOC2L represents a novel HDAC-independent inhibitor of histone acetyltransferase (INHAT);(Hublitz et al., 2005 (PubMed 16322561)).
Synonyms

NOC2L; nucleolar complex associated 2 homolog (S. cerevisiae); nucleolar complex protein 2 homolog; DKFZP564C186; NET7; NET15; NOC2-like protein; protein NOC2 homolog; novel INHAT repressor; novel INHAT (inhibitor of histone acetyltransferase) repressor;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NOC2L-940H	Recombinant Human NOC2L	Mammalian Cell	His		Inquiry
Human	NOC2L-3774HCL	Recombinant Human NOC2L 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NOC2L-301414H	Recombinant Human NOC2L protein, GST-tagged	E.coli	GST	Met1-Ala202	Inquiry
Human	NOC2L-6677HF	Recombinant Full Length Human NOC2L Protein, GST-tagged	In Vitro Cell Free System	GST	749 amino acids	Inquiry
Human	NOC2L-3647H-B	Recombinant Human NOC2L Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	NOC2L-5961H	Recombinant Human NOC2L Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	NOC2L-3647H	Recombinant Human NOC2L Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	NOC2L-1121Z	Recombinant Zebrafish NOC2L	Mammalian Cell	His		Inquiry
Chicken	NOC2L-2567C	Recombinant Chicken NOC2L	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NOC2L involved in several pathways and played different roles in them. We selected most pathways NOC2L participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NOC2L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NOC2L has several biochemical functions, for example, chromatin binding, histone binding, nucleosome binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NOC2L itself. We selected most functions NOC2L had, and list some proteins which have the same functions with NOC2L. You can find most of the proteins on our site.

Function	Related Protein
chromatin binding	HOXC13;HOXD10;OVOL2;CHAF1B;AJUBA;PAX3;CHAF1A;CREB3;NR5A2
histone binding	PRMT6;USP16;WDTC1;HIST4H4;PRKCB;SPTY2D1;PKN1;BRD7;UIMC1
nucleosome binding	ARID1A;DNTTIP1;ZNHIT1;NOC2L;RNF169;L3MBTL1;RNF168;MUM1;RNF4
poly(A) RNA binding	RPS24;AKAP8;RPF1;CCDC9;NPM1;XRN2;YWHAE;CPEB2;PRAC
protein binding	CAP2;TRAPPC3;AP3S1;ARMCX1;VEPH1;TDG;ATP7B;TLR2;ANKFY1
repressing transcription factor binding	RUNX2;TLE4;DDX20;EIF4E;HDAC7A;SRI;HDAC5;NFYB;KAT5
transcription corepressor activity	NPAT;AEBP1;C1D;IRF2BP2;KLF12;YAP1;PPP1R13L;RCOR2;SIAH2

NOC2L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOC2L here. Most of them are supplied by our site. Hope this information will be useful for your research of NOC2L.

TP53; ATXN7; GIPC1; MYC; HIST1H3D; H3F3A; ILK; HIST2H3D; BRF2; PHLDA3; MAGED1; ftsZ