NOX1
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Official Full Name
NADPH oxidase 1
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Overview
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene. -
Synonyms
NOX1; NADPH oxidase 1; GP91 2; mitogenic oxidase (pyridine nucleotide dependent superoxide generating); MOX1; NADPH oxidase 1 variant NOH 1L; NADPH oxidase homolog 1; NOH 1; NOH1; MOX-1; NOX-1; mitogenic oxidase 1; NADPH oxidase homolog-1;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Homo sapiens (Human)
- Human
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- In vitro E. coli expression system
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|T7
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | NOX1-1335H | Recombinant Human NOX1, His-tagged | E.coli | His | 292-560aa | |
Human | NOX1-1359H | Recombinant Human NOX1 protein, His-tagged | E.coli | His | Met235~Asn488 | |
Human | NOX1-404H | Recombinant Human NOX1 | Mammalian Cell | His | ||
Human | NOX1-3751HCL | Recombinant Human NOX1 293 Cell Lysate | HEK293 | N/A | ||
Human | NOX1-3659H | Recombinant Human NOX1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | NOX1-1329H | Recombinant Human NOX1 Full Length Transmembrane protein, His-tagged | In vitro E. coli expression system | His | 1-564aa | |
Human | NOX1-3659H-B | Recombinant Human NOX1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | NOX1-4191H | Recombinant Human NOX1 Protein (Arg54-Glu283), N-His tagged | E.coli | N-His | Arg54-Glu283 | |
Mouse | NOX1-10797M | Recombinant Mouse NOX1 Protein | Mammalian Cell | His | ||
Mouse | NOX1-6146M | Recombinant Mouse NOX1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | NOX1-6146M-B | Recombinant Mouse NOX1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | NOX1-4030R | Recombinant Rat NOX1 Protein | Mammalian Cell | His | ||
Rat | Nox1-2796R | Recombinant Rat Nox1 protein, His & T7-tagged | E.coli | His/T7 | Arg291~Arg544 (Accession # Q9WV87) | |
Rat | NOX1-3689R | Recombinant Rat NOX1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | NOX1-3689R-B | Recombinant Rat NOX1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Homo sapiens (Human) | RFL13066HF | Recombinant Full Length Human Nadph Oxidase 1(Nox1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-564aa) | |
Mus musculus (Mouse) | RFL32513MF | Recombinant Full Length Mouse Nadph Oxidase 1(Nox1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-591) | |
Rattus norvegicus (Rat) | RFL7282RF | Recombinant Full Length Rat Nadph Oxidase 1(Nox1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-563) | |
Zebrafish | NOX1-5913Z | Recombinant Zebrafish NOX1 | Mammalian Cell | His | ||
Chicken | NOX1-3741C | Recombinant Chicken NOX1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- NOX1 Related Articles
NOX1 involved in several pathways and played different roles in them. We selected most pathways NOX1 participated on our site, such as HIF- signaling pathway, Phagosome, Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with NOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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HIF- signaling pathway | PRKCG;Trf;INSR;PDK1;BCL2;IGF1R;CAMK2G;RELA;Il6ra |
Phagosome | ATP6V1C1A;SFTPA1;C3A.2;ATP6V0A1B;H2-Q10;ATP6V1E1B;TUBAL3;THBS4B;BLB1 |
Osteoclast differentiation | TRAF6;SFPI1;TNFRSF11A;LILRA4;TGFBR2;TYROBP;FCGR4;IFNGR2;GRB2 |
Leukocyte transendothelial migration | MAPK11;RAP1B;OCLN;MYL12B;CLDN6;CLDN11;ITGAM;CLDN14;VAV3 |
NOX1 has several biochemical functions, for example, NADP binding, Rac GTPase binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NOX1 itself. We selected most functions NOX1 had, and list some proteins which have the same functions with NOX1. You can find most of the proteins on our site.
Function | Related Protein |
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NADP binding | GAPDHS;GSR;ASPDH;NNT;HMGCRB;CRYM;FMO5;FMO2;G6PD |
Rac GTPase binding | DVL1;SRGAP2A;SRGAP1;PKN1;PAK7;CDKL5;RAB7;CAV1;PAK3 |
metal ion binding | SAP30L;GTPBP8;ZNF485;ZNF800;ZNF776;CD209;SEC23IP;ZFP426;TET3 |
protein binding | ATP4B;KCNA3;TNS4;ELK1;Apba1;TET3;CYBRD1;DOHH;ASMTL |
superoxide-generating NADPH oxidase activity | NOX3;NCF1;NOX1;NOX4;PAX2;CYBB;NOX5;SH3PXD2AA |
voltage-gated proton channel activity | NOX1;HVCN1 |
NOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NOX1.
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