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NOX5

Official Full Name

NADPH oxidase, EF-hand calcium binding domain 5
Overview

This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms

NOX5; NADPH oxidase, EF-hand calcium binding domain 5; NADPH oxidase 5; NOX5A; NOX5B; MGC149776; MGC149777;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Homo sapiens (Human)
Human

Source

E.coli
E.coli expression system
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His|T7
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NOX5-2797H	Recombinant Human NOX5 protein, His & T7-tagged	E.coli	His/T7	Ser456~Phe765 (Accession # Q96PH1)	Inquiry
Human	NOX5-3750HCL	Recombinant Human NOX5 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NOX5-6009H	Recombinant Human NOX5 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	NOX5-5176H	Recombinant Human NOX5 Protein (Ser456-Phe765), N-His tagged	E.coli	N-His	Ser456-Phe765	Inquiry
Human	NOX5-6723HF	Recombinant Full Length Human NOX5 Protein, GST-tagged	In Vitro Cell Free System	GST	747 amino acids	Inquiry
Homo sapiens (Human)	RFL11578HF	Recombinant Full Length Human Nadph Oxidase 5(Nox5) Protein, His-Tagged	E.coli expression system	His	Full Length (1-765)	Inquiry
Chicken	NOX5-3726C	Recombinant Chicken NOX5	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NOX5 involved in several pathways and played different roles in them. We selected most pathways NOX5 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NOX5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

NOX5 has several biochemical functions, for example, NADP binding, calcium ion binding, flavin adenine dinucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NOX5 itself. We selected most functions NOX5 had, and list some proteins which have the same functions with NOX5. You can find most of the proteins on our site.

Function	Related Protein
NADP binding	NNT;CRYZL1;FMO1;FMO5;DHFRL1;SPR;PGD;FMO2;NDOR1
calcium ion binding	IHH;PCDH2G10;SLIT3;S100A7A;LTBP1;MAN1B1;PCDH2G1;DGKAA;CLSTN3
flavin adenine dinucleotide binding	TXNRD2;DUS1L;FMO2;FOXRED2;CYB5R3;KMO;ACOX3;TXNRD1;MAOB
heme binding	CYP51A1;CYP3C1;FA2H;HBB-BH1;CYP2C54;CYP2V1;HBA1;CYP2N13;CYP2AD2
hydrogen ion channel activity	ACCN5;SLC4A11;NOX5;ASIC5
protein binding	SREBF2;NDRG1;COBRA1;CREBBP;COPS5;TDRD1;BRIP1;IL10RA;GATAD2B
superoxide-generating NADPH oxidase activity	NOX4;NOX5;NOX1;NOX3;CYBB;NCF1;PAX2;SH3PXD2AA

NOX5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NOX5 here. Most of them are supplied by our site. Hope this information will be useful for your research of NOX5.