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NPHP1

Official Full Name

nephronophthisis 1 (juvenile) homolog (human)
Overview

Nephrocystin-1 is a protein that in humans is encoded by the NPHP1 gene.
Synonyms

NPHP1; nephronophthisis 1 (juvenile) homolog (human); nephrocystin-1; JBTS4; Juvenile nephronophthisis 1 protein; Nephrocystin 1; NPH1; SLSN1;

Type

Cell & Tissue Lysates
Recombinant Proteins

Species

Chicken
Human
Zebrafish

Source

E.coli
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NPHP1-1210HCL	Recombinant Human NPHP1 cell lysate		N/A		Inquiry
Human	NPHP1-688H	Recombinant Human NPHP1 Protein (1-109 aa), GST-tagged	E.coli	GST	1-109 aa	Inquiry
Human	NPHP1-6620HF	Recombinant Full Length Human NPHP1 Protein, GST-tagged	In Vitro Cell Free System	GST	121 amino acids	Inquiry
Human	NPHP1-3643H	Recombinant Human NPHP1 protein, GST-tagged	E.coli	GST	1-48 aa	$319 / 25ug
Human	NPHP1-6026H	Recombinant Human NPHP1 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Zebrafish	NPHP1-4626Z	Recombinant Zebrafish NPHP1	Mammalian Cell	His		Inquiry
Chicken	NPHP1-4301C	Recombinant Chicken NPHP1	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NPHP1 involved in several pathways and played different roles in them. We selected most pathways NPHP1 participated on our site, such as Anchoring of the basal body to the plasma membrane, Assembly of the primary cilium, Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPHP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Anchoring of the basal body to the plasma membrane	NINL;OFD1;NPHP1;TCTN1;CDK5RAP2;B9D1;MAPRE1B;MAPRE1;CC2D2A
Assembly of the primary cilium	TCTEX1D1;NPHP3;CLUAP1;ARF4;MKKS;ACTR1A;IQCB1;DCTN1A;TNPO1
Organelle biogenesis and maintenance	MRPL40;TCTN3;MRPS25;GABPA;RAB3IP;MRPL3;EXOC6;TTC30A;TTC8

NPHP1 has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NPHP1 itself. We selected most functions NPHP1 had, and list some proteins which have the same functions with NPHP1. You can find most of the proteins on our site.

Function	Related Protein
protein binding	HACL1;CAMK2B;GBA;VPS41;FOXRED2;TFAP4;FAM193B;LRCH1;SETD6
structural molecule activity	KRT25;KRT1-C5;CLDN22;CLDN2;FLG;CLDN7B;SPRR2D;BVES;MAP1B

NPHP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPHP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NPHP1.

PKD1; ADAM15; AHI1; ASAP1; K15-M; MED28; UBQLN4