NPSR1

Official Full Name

neuropeptide S receptor 1

Background

This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Synonyms

NPSR1; neuropeptide S receptor 1; G protein coupled receptor 154 , GPR154; neuropeptide S receptor; GPRA; PGR14; ASRT2; G protein coupled receptor 154; G protein coupled receptor for asthma susceptibility; G protein coupled receptor PGR14; GPR 154; gpr154; MVTR; nps receptor; NPSR 1; NPSR; PGR 14; Vasopressin receptor related receptor 1; VRR 1; VRR1; G protein-coupled receptor 154; G-protein coupled receptor 154; G-protein coupled receptor PGR14; vasopressin receptor-related receptor 1; G protein-coupled receptor for asthma susceptibility; G-protein coupled receptor for asthma susceptibility