NPSR1
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Official Full Name
neuropeptide S receptor 1
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Overview
This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Mutations in this gene have also been associated with this disease. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] -
Synonyms
NPSR1; neuropeptide S receptor 1; GPRA; NPSR; VRR1; ASRT2; PGR14; GPR154; neuropeptide S receptor; G protein-coupled receptor 154; G-protein coupled receptor 154; G-protein coupled receptor PGR14; G protein-coupled receptor for asthma susceptibility; G-protein coupled receptor for asthma susceptibility;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Homo sapiens (Human)
- Human
- Macaca mulatta (Rhesus macaque)
- Mus musculus (Mouse)
- Rattus norvegicus (Rat)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NPSR1-1348H | Recombinant Human NPSR1, GST-tagged | E.coli | GST | 1-52aa | |
| Human | NPSR1-3728HCL | Recombinant Human NPSR1 293 Cell Lysate | HEK293 | N/A |
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| Human | NPSR1-5196H | Recombinant Human NPSR1 Protein, GST-tagged | Wheat Germ | GST |
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| Human | NPSR1-6648HF | Recombinant Full Length Human NPSR1 Protein | In Vitro Cell Free System | 224 amino acids |
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| Human | NPSR1-6047H | Recombinant Human NPSR1 Protein | Wheat Germ | N/A |
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| Homo sapiens (Human) | RFL22148HF | Recombinant Full Length Human Neuropeptide S Receptor(Npsr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-371) |
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| Macaca mulatta (Rhesus macaque) | RFL32172MF | Recombinant Full Length Macaca Mulatta Neuropeptide S Receptor(Npsr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-371) |
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| Mus musculus (Mouse) | RFL36747MF | Recombinant Full Length Mouse Neuropeptide S Receptor(Npsr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-371) |
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| Rattus norvegicus (Rat) | RFL14224RF | Recombinant Full Length Rat Neuropeptide S Receptor(Npsr1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-372) |
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| Rhesus Macaque | NPSR1-3082R | Recombinant Rhesus monkey NPSR1 Protein, His-tagged | Mammalian Cell | His |
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| Rhesus Macaque | NPSR1-2901R | Recombinant Rhesus Macaque NPSR1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Rhesus Macaque | NPSR1-2901R-B | Recombinant Rhesus Macaque NPSR1 Protein Pre-coupled Magnetic Beads | HEK293 |
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- Involved Pathway
- Protein Function
- Interacting Protein
NPSR1 involved in several pathways and played different roles in them. We selected most pathways NPSR1 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (q) signalling events, G alpha (s) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPSR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | ADRA2B;NPB;GPR55A;HCAR1-2;PROKR2;CGA;EDNRA;SSTR4;CCL35.2 |
| G alpha (q) signalling events | DGKA;OXTRL;KALRN;CHRM3;HCRT;PROK2;MLN;CASR;GRP |
| G alpha (s) signalling events | RLN3A;ADM2;POMCB;CRH;PTHLH;RLN2;ADM2A;INSL3;DRD5 |
| GPCR downstream signaling | CYSLTR1;HEBP1;RGS7;FPR-RS4;NET1;OPN4;RAMP2;TAE1;OR52B4 |
| GPCR ligand binding | QRFPR;GPR55;OXER1;EDNRB;CYSLTR1;NMBB;CRHR1;GPR37B;EDNRAB |
| Gastrin-CREB signalling pathway via PKC and MAPK | FPR-RS6;GCGB;TAC3;RGS21;TRPC7;PROKR1;GPR132;PMCH;NMB |
| Peptide ligand-binding receptors | AMCF-II;PNOCB;CCRL2;SSTR4;PROKR1A;TAC2;GPR37B;NMBA;QRFP |
| Signal Transduction | BCL9L;ARHGAP17B;TLE2;RBP2A;PDK2B;ADAM12;LPAR2B;DHRS4;LRP10 |
NPSR1 has several biochemical functions, for example, neuropeptide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NPSR1 itself. We selected most functions NPSR1 had, and list some proteins which have the same functions with NPSR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| neuropeptide receptor activity | NPSR1;NPBWR1;SORCS2;NPFFR1L1;NPFFR1;NPFFR2;NPBWR2;MCHR1;SORCS3 |
NPSR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPSR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NPSR1.
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