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NPY1R

  • Official Full Name

    neuropeptide Y receptor Y1

  • Overview

    Neuropeptide Y (NPY; MIM 162640) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits;a diverse range of important physiologic activities, including effects on psychomotor activity, food intake,;regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. Two major;subtypes of NPY (Y1 and Y2) have been defined by pharmacologic criteria. NPY receptors, such as NPY1R, have been;identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, and aortic;smooth muscle (Herzog et al., 1992 (PubMed 1321422)).
  • Synonyms

    NPY1R; neuropeptide Y receptor Y1; NPYR; neuropeptide Y receptor type 1; NPY1-R;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Cavia porcellus (Guinea pig)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Sus scrofa (Pig)
  • Xenopus laevis (African clawed frog)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Flag
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NPY1R-1351H Recombinant Human NPY1R, GST-tagged E.coli GST 310-384aa
Human NPY1R-1214HCL Recombinant Human NPY1R cell lysate N/A
Human NPY1R-6055H Recombinant Human NPY1R Protein Wheat Germ N/A
Human NPY1R-6655HF Recombinant Full Length Human NPY1R Protein In Vitro Cell Free System 113 amino acids
Human NPY1R-1038HFL Recombinant Human NPY1R protein, His&Flag-tagged HEK293 His&Flag 1-384 aa
Human NPY1R-6657HF Recombinant Full Length Human NPY1R Protein, GST-tagged In Vitro Cell Free System GST 384 amino acids
Human NPY1R-6056H Recombinant Human NPY1R Protein, GST-tagged Wheat Germ GST
Human NPY1R-4736H Recombinant Human NPY1R Protein (Phe282-Ile384), N-GST tagged E.coli N-GST Phe282-Ile384
Human NPY1R-2505H Recombinant Human NPY1R Protein, His-tagged E.coli N-His Phe282-Ile384
Mouse NPY1R-10846M Recombinant Mouse NPY1R Protein Mammalian Cell His
Mouse NPY1R-6177M-B Recombinant Mouse NPY1R Protein Pre-coupled Magnetic Beads HEK293
Mouse NPY1R-6177M Recombinant Mouse NPY1R Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL36198BF Recombinant Full Length Bovine Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-383)
Canis lupus familiaris (Dog) (Canis familiaris) RFL20666CF Recombinant Full Length Dog Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-382)
Cavia porcellus (Guinea pig) RFL15569CF Recombinant Full Length Guinea Pig Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-383)
Homo sapiens (Human) RFL27176HF Recombinant Full Length Human Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Mus musculus (Mouse) RFL1500MF Recombinant Full Length Mouse Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-382)
Rattus norvegicus (Rat) RFL34170RF Recombinant Full Length Rat Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-382)
Rhesus Macaque NPY1R-3087R Recombinant Rhesus monkey NPY1R Protein, His-tagged Mammalian Cell His
Rhesus Macaque NPY1R-2906R Recombinant Rhesus Macaque NPY1R Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque NPY1R-2906R-B Recombinant Rhesus Macaque NPY1R Protein Pre-coupled Magnetic Beads HEK293
Sus scrofa (Pig) RFL244SF Recombinant Full Length Pig Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-383)
Xenopus laevis (African clawed frog) RFL10154XF Recombinant Full Length Xenopus Laevis Neuropeptide Y Receptor Type 1(Npy1R) Protein, His-Tagged E.coli expression system His Full Length (1-366)
Zebrafish NPY1R-5917Z Recombinant Zebrafish NPY1R Mammalian Cell His
Chicken NPY1R-3179C Recombinant Chicken NPY1R Mammalian Cell His
Kit-1443 NPY1R CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-0957 TR-FRET Progesterone Receptor Coactivator Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NPY1R Related Articles

NPY1R involved in several pathways and played different roles in them. We selected most pathways NPY1R participated on our site, such as cAMP signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPY1R were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
cAMP signaling pathwayCALM4;CAMK2D;PIK3R1;HTR1A;CALM2;NFKBIA;GRIN1;PIK3CB;HTR1F
Neuroactive ligand-receptor interactionTAAR14A;THRAA;THRA;Gh;GLRA3;DRD4B;P2RY14;GABRR1;TACR1B
Regulation of lipolysis in adipocytesIRS4;PNPLA2;INS1;AKT2;PRKACA;GNAI3;GNAS;PTGS2;GNAI1

NPY1R has several biochemical functions, for example, neuropeptide Y receptor activity, pancreatic polypeptide receptor activity, peptide YY receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NPY1R itself. We selected most functions NPY1R had, and list some proteins which have the same functions with NPY1R. You can find most of the proteins on our site.

Function Related Protein
neuropeptide Y receptor activityPROKR2;PRLHR2A;PRLHR2B;PRLH2R;NPY5R;NPY8AR;PROKR1;PRLHR;NPY2R
pancreatic polypeptide receptor activityNPY1R;NPY8AR;NPY8BR;PPYR1;NPY5R
peptide YY receptor activityNPY2R;PPYR1;NPY1R;NPY5R
protein bindingC1QTNF9B-AS1;KIAA1274;EIF3G;CLIC1;NITR9;ATP7B;VPS72;POLD1;C2orf29

NPY1R has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPY1R here. Most of them are supplied by our site. Hope this information will be useful for your research of NPY1R.

GALR2; NPY; PYY; ATP13A2; LSM7

Xiang, Q; Wang, CL; et al. Interaction of Somatostatin receptor-2 and Neuropeptide Y receptor-1 in mice dorsal root ganglion neurons on the Pinch-nerve injury model (Retracted article. See vol. 110, pg. 273, 2013). PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR 105:71-75(2013).
Singh, S; Metz, I; et al. Microglial nodules in early multiple sclerosis white matter are associated with degenerating axons. ACTA NEUROPATHOLOGICA 125:595-608(2013).
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