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NR4A1

  • Official Full Name

    nuclear receptor subfamily 4, group A, member 1

  • Overview

    Nur77, also known as TR3 and NGFI-B, is an immediate-early response gene and an orphan member of the steroid/thyroid/retinoid receptor superfamily (1-3). Nur77 is composed of an amino-terminal transactivation domain, a central DNA-binding domain and a car
  • Synonyms

    NR4A1; nuclear receptor subfamily 4, group A, member 1; nuclear receptor subfamily 4 group A member 1; hormone receptor; nuclear protein N10; orphan nuclear receptor HMR; nuclear hormone receptor NUR/77; Hmr; N10; TR3; Gfrp; Hbr1; NP10; TIS1; GFRP1; Hbr-1; NGFIB; nur77; NGFI-B;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NR4A1-28049TH Recombinant Human NR4A1 Wheat Germ N/A 598 amino acids
Human NR4A1-12H Recombinant Human NR4A1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NR4A1-1360H Recombinant Human NR4A1, GST-tagged E.coli GST C-term-300aa
Human NR4A1-30494TH Recombinant Human NR4A1 Wheat Germ N/A 598 amino acids
Human NR4A1-1219HCL Recombinant Human NR4A1 cell lysate N/A
Human NR4A1-3287H Recombinant Human NR4A1 protein, His-tagged E.coli His 299-598 aa
Human NR4A1-6744HF Recombinant Full Length Human NR4A1 Protein, GST-tagged In Vitro Cell Free System GST 598 amino acids
Human NR4A1-6093H Recombinant Human NR4A1 Protein, GST-tagged Wheat Germ GST
Human NR4A1-348HF Recombinant Full Length Human NR4A1 Protein In Vitro Cell Free System 598 amino acids
Human NR4A1-61HFL Recombinant Full Length Human NR4A1 Protein, C-Flag-tagged Mammalian cells Flag
Human NR4A1-02H Recombinant Human NR4A1 (351S) Protein, His tagged E.coli His
Human NR4A1-4396H Recombinant Human NR4A1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NR4A1-1541H Recombinant Human NR4A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NR4A1-1541H-B Recombinant Human NR4A1 Protein Pre-coupled Magnetic Beads HEK293
Mouse NR4A1-10871M Recombinant Mouse NR4A1 Protein Mammalian Cell His
Mouse NR4A1-6189M Recombinant Mouse NR4A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse NR4A1-6189M-B Recombinant Mouse NR4A1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Nr4a1-1143M Recombinant Mouse Nr4a1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat NR4A1-4070R Recombinant Rat NR4A1 Protein Mammalian Cell His
Rat NR4A1-3729R Recombinant Rat NR4A1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Nr4a1-1855R Recombinant Rat Nr4a1 Protein, His-tagged E.coli N-His Gly264-Pro352
Rat NR4A1-3729R-B Recombinant Rat NR4A1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish NR4A1-394Z Recombinant Zebrafish NR4A1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NR4A1 involved in several pathways and played different roles in them. We selected most pathways NR4A1 participated on our site, such as MAPK signaling pathway, PIK-Akt signaling pathway, Aldosterone synthesis and secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR4A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MAPK signaling pathwayEGFRA;MAPK13;CACNG8;MAP3K2;PRKCBB;SOS1;TNF;TNFRSF1A;MAP4K2
PIK-Akt signaling pathwayAKT2;PPP2R2A;GNB4;YWHAB;ITGA9;IFNA16;PIK3R2;PDGFD;ITGB5
Aldosterone synthesis and secretionCYP21A2;KCNK9;CREB3L1;GNAS;SLC14A2;ADCY6;PRKD3;LIPE;KCNK3

NR4A1 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR4A1 itself. We selected most functions NR4A1 had, and list some proteins which have the same functions with NR4A1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingPOT1A;LHX2B;POLR2K;ISL2;EPAS1B;UNCX;ZNF556;EXO5;CEBPA
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingVDRA;NR2F1B;RORA;NR2F6A;NR2F1A;AHR;NR2F1;PPARAA;NR4A2A
protein bindingMED26;TCERG1;C7orf31;HSPB6;GYPC;MMS22L;ANKHD1;RGS17;COLGALT2
protein heterodimerization activitySOX4;NFYBB;RARA;HIST3H2A;TENM2;HIST2H3C;JDP2;ATF4;DMRT3
sequence-specific DNA bindingLHX4;FOXN4;DBX1A;FOXD4L1;RARAB;MSXD;HOXA4;RORCA;LMX1B
steroid hormone receptor activityPGR;NR1D2A;RXRGB;RXRB;NR4A3;PPARAB;RXRBB;NR1D4B;RORCA
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingNCOA3;CEBPG;MEOX2;SMAD2;SMAD1;TFAP2C;ELK3;BCL11B;PAX8
zinc ion bindingSIVA1;RFPL4B;ALKBH8;TRAF6;ZMIZ2;PIAS1;WHSC1L1;ISL2A;TADA2B

NR4A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR4A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR4A1.

BCL2; TP53; GK; 386677

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