Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

NRF1

  • Official Full Name

    nuclear respiratory factor 1

  • Overview

    This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression;of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis,;and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of;neurite outgrowth. Alternate transcriptional splice variants, which encode the same protein, have been characterized.;Additional variants encoding different protein isoforms have been described but they have not been fully;characterized. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and;for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1.
  • Synonyms

    NRF1; nuclear respiratory factor 1; alpha palindromic binding protein; ALPHA PAL; EWG; NRF-1; alpha palindromic-binding protein; ALPHA-PAL;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|MBP
  • His|SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NRF1-358H Recombinant Human NRF1 protein, His/MBP-tagged E.coli His/MBP 40-279 aa
Human NRF1-2152H Recombinant Human NRF1, MYC/DDK-tagged HEK293 Myc/DDK
Human NRF1-30415TH Recombinant Human NRF1 Wheat Germ N/A 85 amino acids
Human NRF1-3698HCL Recombinant Human NRF1 293 Cell Lysate HEK293 N/A
Human NRF1-3699HCL Recombinant Human NRF1 293 Cell Lysate HEK293 N/A
Human NRF1-1538H Recombinant Human NRF1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NRF1-564HFL Recombinant Full Length Human NRF1 Protein, C-Flag-tagged Mammalian cells Flag
Human NRF1-1546H-B Recombinant Human NRF1 Protein Pre-coupled Magnetic Beads HEK293
Human NRF1-1546H Recombinant Human NRF1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NRF1-8765HFL Recombinant Full Length Human NRF1, Flag-tagged Mamanlian cells Flag
Mouse Nrf1-5488M Recombinant Mouse Nrf1 protein, His-tagged Yeast His 1-503aa
Mouse NRF1-1800M Recombinant Mouse NRF1 Protein (1-503 aa), His-SUMO-tagged E.coli His/SUMO 1-503 aa
Mouse NRF1-1859M Recombinant Mouse NRF1 Protein (1-503 aa), His-SUMO-tagged Yeast His/SUMO 1-503 aa
Mouse Nrf1-4499M Recombinant Mouse Nrf1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) RFL27048SF Recombinant Full Length Schizosaccharomyces Pombe Vacuolar Transporter Chaperone 1(Nrf1) Protein, His-Tagged E.coli expression system His Full Length (1-122)
Zebrafish NRF1-9207Z Recombinant Zebrafish NRF1 Mammalian Cell His
Chicken NRF1-2353C Recombinant Chicken NRF1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NRF1 Related Articles
  • NRF1 Related Research Area

NRF1 involved in several pathways and played different roles in them. We selected most pathways NRF1 participated on our site, such as Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Huntingtons diseaseDNAL4;TBP;TBPL2;POLR2G;CREB3L3;NDUFB11;TAF4B;SDHB;SP1

NRF1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, core promoter sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRF1 itself. We selected most functions NRF1 had, and list some proteins which have the same functions with NRF1. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA bindingGATA4;YBX1;POU4F3;IFI203;MXD1;BCL11A;SOX10;STAT3;SIX4
core promoter sequence-specific DNA bindingCHD2;SIRT1;ATF4;NR4A3;C1orf51;PRMT5;TRP53;KLF10;SOX1
protein bindingBIRC2;ATM;PDE3B;COPG;IGFBP2;DPYSL2;KDR;AARSD1;PIH1D3
protein homodimerization activityTERFA;SETMAR;PITX2;GOLGA5;ENO2;NRF1;ASGR1;IKZF3;LSM1
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific bindingFIGLA;PLAG1;HOXC11;BARHL2;FOXJ1;NRF1;CREB1;ETV4;SRF

NRF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NRF1.

SP4; TRAF2; FHL2; POGZ; PB1; PB1; sph

Zhao, WW; Ma, GX; et al. Lipopolysaccharide induced LOX-1 expression via TLR4/MyD88/ROS activated p38MAPK-NF-kappa B pathway. VASCULAR PHARMACOLOGY 63:162-172(2014).
Sotgia, F; Whitaker-Menezes, D; et al. Mitochondria "fuel" breast cancer metabolism Fifteen markers of mitochondrial biogenesis label epithelial cancer cells, but are excluded from adjacent stromal cells. CELL CYCLE 11:4390-4401(2012).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All NRF1 Products

Required fields are marked with *

My Review for All NRF1 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends