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NRTN

Official Full Name

neurturin
Overview

Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Jul 2008]
Synonyms

NRTN; neurturin; NTN; prepro-neurturin;

Type

Recombinant Proteins
GMP Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E. coli
E.coli
HEK293
Mammalian Cell

Tag

C
His
His (Fc)
Avi
His(C
ter)
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NRTN-750H	Active Recombinant Human NRTN Protein	E.coli	N/A		Inquiry
Human	NRTN-953H	Recombinant Human Neurturin	E.coli	N/A		Inquiry
Human	NRTN-29535TH	Recombinant Human NRTN protein	E.coli	N/A	102	Inquiry
Human	NRTN-259H	Recombinant Active Human NRTN Protein, His-tagged(C-ter)	E.coli	His(C-ter)		Inquiry
Human	NRTN-090H	Active Recombinant Human NRTN Protein	E. coli			Inquiry
Human	NRTN-236H	Active Recombinant Human NRTN Protein (Ala96-Val197), C-His tagged, Animal-free, Carrier-free	E.coli	C-His	Ala96-Val197	Inquiry
Mouse	Nrtn-01M	Active GMP Recombinant Mouse Nrtn Protein, His-Tagged	E.coli	His		Inquiry
Mouse	NRTN-10902M	Recombinant Mouse NRTN Protein	Mammalian Cell	His		Inquiry
Mouse	NRTN-6214M-B	Recombinant Mouse NRTN Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	NRTN-6214M	Recombinant Mouse NRTN Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Nrtn-72M	Active Recombinant Mouse Nrtn Protein (Cys101-Val195), N-His tagged, Animal-free, Carrier-free	E.coli	N-His	Cys101-Val195	Inquiry
Chicken	NRTN-3655C	Recombinant Chicken NRTN	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
NRTN Related Research Area

NRTN involved in several pathways and played different roles in them. We selected most pathways NRTN participated on our site, such as Axon guidance, Developmental Biology, NCAM signaling for neurite out-growth, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRTN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Axon guidance	EFNA3B;LIMK2;ACTR2B;DOCK1;EVL;ABL1;SPRED3;PLXNC1;SEMA3AB
Developmental Biology	SPRED1;FGFR1B;MED20;NR6A1;KIF4A;MED31;NADL1.1;PITPNA;DNM2
NCAM signaling for neurite out-growth	GFRA2;NRTN;PSPN;COL9A1B;COL9A1A;GFRA4;GFRA1;ST8SIA2;GDNF
NCAM1 interactions	NRTN;GDNF;COL9A1B;GFRA1;GFRA2;GFRA4;PSPN;COL9A1A

NRTN has several biochemical functions, for example, growth factor activity, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRTN itself. We selected most functions NRTN had, and list some proteins which have the same functions with NRTN. You can find most of the proteins on our site.

Function	Related Protein
growth factor activity	KITLG;VEGFC;IGF2;BMP2B;REG1A;BMP4;TGFB2;MSTN;FGF1A
receptor binding	FGF11A;HFE2;PTK2AA;CXCL1;HTT;RND1;ARPP19;CAT;ANGPTL2

NRTN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRTN here. Most of them are supplied by our site. Hope this information will be useful for your research of NRTN.

GDNF Family Ligands